Component
Preterm infant weight-gain velocity
Preterm infant weight-gain velocity. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Mean weight-gain velocity was 26.9 versus 22.9 g/kg/day with supplementation versus placebo.
Experimental context and source evidence
- availability_state
- nutrient_deficiency Imported condition classification; unverified.
- evidence_span
- {"source_cache": "artifacts/sodium-research/25406227.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "a3c6cd28e4896dc8cdaeaacb7d524c55098b87dd5bf9d028ce49ba544832e339", "start_char": 0, "end_char": 1645, "text_sha256": "a3c6cd28e4896dc8cdaeaacb7d524c55098b87dd5bf9d028ce49ba544832e339"}
- experimental_model
- Randomized masked trial in 53 infants born before 32 weeks
- exposure
- 4 mEq/kg/day supplemental sodium versus placebo, days 7–35
- limitations
- Study regimen, not a dosing recommendation. Small neonatal trial; improved weight gain is not proof that every blood sodium measurement diagnoses total-body depletion.
- nutrient_topic
- Sodium research collection; topical membership is not evidence of a direct dietary effect. · Sodium
- organism
- Human preterm infants
- plain_language
- The sodium intervention improved weight gain in this small preterm-infant trial.
- primary_references
- [sodium-p25406227] Impact of Early Sodium Supplementation on Hyponatremia and Growth in Premature Infants: A Randomized Controlled Trial. (2016). https://pubmed.ncbi.nlm.nih.gov/25406227/ DOI: 10.1177/0148607114558303
- tissue_or_cell_type
- Whole-body growth and serum sodium
- trigger_kind
- nutrient_deficiency Imported condition classification; unverified.
Sodium: gradients, nutrient transport, fluid regulation and loss states (2026-09-17) · lines 980–991
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized masked trial in 53 infants born before 32 weeks · source_derived_draft · unverified_draft
### sodium-preterm-weight Mean weight-gain velocity was 26.9 versus 22.9 g/kg/day with supplementation versus placebo. Condition category: nutrient_deficiency nutrient_topic: Sodium research collection; topical membership is not evidence of a direct dietary effect. plain_language: The sodium intervention improved weight gain in this small preterm-infant trial. organism: Human preterm infants tissue_or_cell_type: Whole-body growth and serum sodium experimental_model: Randomized masked trial in 53 infants born before 32 weeks limitations: Study regimen, not a dosing recommendation. Small neonatal trial; improved weight gain is not proof that every blood sodium measurement diagnoses total-body depletion. exposure: 4 mEq/kg/day supplemental sodium versus placebo, days 7–35 evidence_span: {"source_cache": "artifacts/sodium-research/25406227.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "a3c6cd28e4896dc8cdaeaacb7d524c55098b87dd5bf9d028ce49ba544832e339", "start_char": 0, "end_char": 1645, "text_sha256": "a3c6cd28e4896dc8cdaeaacb7d524c55098b87dd5bf9d028ce49ba544832e339"} [sodium-p25406227] Impact of Early Sodium Supplementation on Hyponatremia and Growth in Premature Infants: A Randomized Controlled Trial. (2016). https://pubmed.ncbi.nlm.nih.gov/25406227/ DOI: 10.1177/0148607114558303
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.