Component
Plasma triglyceride concentration
Plasma triglyceride concentration. Species, exposure and limitations are retained in each linked claim.
2 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Fasting triglycerides were higher in the low-chromium group than the normal-chromium group at the end of the rat experiment.
Experimental context and source evidence
- availability_state
- nutrient_deficiency Imported condition classification; unverified.
- evidence_span
- {"source_cache": "artifacts/chromium-research/36701335.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "762bdd075019b97831308c39060063214abcb5c5075bfc69afd9b1e250b41a48", "start_char": 0, "end_char": 1806, "text_sha256": "762bdd075019b97831308c39060063214abcb5c5075bfc69afd9b1e250b41a48"}
- experimental_model
- Twelve-week dietary chromium experiment in both sexes
- exposure
- From day 35 of age; moderately high-fat/high-sucrose diets with 0.33, 1.20 or 9.15 mg Cr/kg; 10 males and 10 females/group
- limitations
- Different diet, strain and duration from the 2011 study. Greater food intake can contribute to adiposity and insulin changes. Low is relative to this rodent formulation, not a human deficiency cutoff.
- nutrient_topic
- Chromium research collection; topical membership is not evidence of a direct dietary effect. · Chromium
- organism
- Sprague-Dawley CD rats
- plain_language
- The lower-chromium diet also changed a circulating lipid measurement.
- primary_references
- [chromium-p36701335] A low chromium diet increases body fat, energy intake and circulating triglycerides and insulin in male and female rats fed a moderately high-fat, high-sucrose diet from peripuberty to young adult age. (2023). https://pubmed.ncbi.nlm.nih.gov/36701335/ DOI: 10.1371/journal.pone.0281019
- tissue_or_cell_type
- Whole-body fat and circulating metabolic measures
- trigger_kind
- nutrient_deficiency Imported condition classification; unverified.
Chromium: transport, insulin signaling, nutrient interactions and essentiality debate (2026-09-17) · lines 1004–1015
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Twelve-week dietary chromium experiment in both sexes · source_derived_draft · unverified_draft
### chromium-low-diet-triglycerides-2023 Fasting triglycerides were higher in the low-chromium group than the normal-chromium group at the end of the rat experiment. Condition category: nutrient_deficiency nutrient_topic: Chromium research collection; topical membership is not evidence of a direct dietary effect. plain_language: The lower-chromium diet also changed a circulating lipid measurement. organism: Sprague-Dawley CD rats tissue_or_cell_type: Whole-body fat and circulating metabolic measures experimental_model: Twelve-week dietary chromium experiment in both sexes limitations: Different diet, strain and duration from the 2011 study. Greater food intake can contribute to adiposity and insulin changes. Low is relative to this rodent formulation, not a human deficiency cutoff. exposure: From day 35 of age; moderately high-fat/high-sucrose diets with 0.33, 1.20 or 9.15 mg Cr/kg; 10 males and 10 females/group evidence_span: {"source_cache": "artifacts/chromium-research/36701335.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "762bdd075019b97831308c39060063214abcb5c5075bfc69afd9b1e250b41a48", "start_char": 0, "end_char": 1806, "text_sha256": "762bdd075019b97831308c39060063214abcb5c5075bfc69afd9b1e250b41a48"} [chromium-p36701335] A low chromium diet increases body fat, energy intake and circulating triglycerides and insulin in male and female rats fed a moderately high-fat, high-sucrose diet from peripuberty to young adult age. (2023). https://pubmed.ncbi.nlm.nih.gov/36701335/ DOI: 10.1371/journal.pone.0281019
Complete structured claim and evidenceBoron supplementation returned elevated plasma triglyceride concentrations in vitamin-D3-inadequate chicks toward those in vitamin-D3-adequate chicks.
Experimental context and source evidence
- availability_state
- nutrient_deficiency Imported condition classification; unverified.
- evidence_span
- {"source_cache": "artifacts/boron-research/8140930.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "6f8776234acbd0efd282761bbbcb0f51b39d8882c651b3f64686a890f646d4fc", "start_char": 0, "end_char": 1621, "text_sha256": "6f8776234acbd0efd282761bbbcb0f51b39d8882c651b3f64686a890f646d4fc"}
- experimental_model
- Factorial boron/vitamin-D3 feeding experiment in chicks
- exposure
- 26 days; basal boron ≤0.18 mg/kg with 0 or 1.4 mg/kg orthoboric acid supplement; vitamin D3 3.13 or 15.6 µg/kg
- limitations
- Animal developmental experiment. It did not demonstrate direct CYP24A1 inhibition or that boron replaces vitamin D in humans.
- nutrient_topic
- Boron research collection; topical membership is not evidence of a direct dietary effect. · Boron
- organism
- Day-old cockerel chicks
- plain_language
- Some metabolic changes from inadequate vitamin D improved in this chick experiment.
- primary_references
- [boron-p8140930] Dietary boron modifies the effects of vitamin D3 nutrition on indices of energy substrate utilization and mineral metabolism in the chick. (1994). https://pubmed.ncbi.nlm.nih.gov/8140930/ DOI: 10.1002/jbmr.5650090206
- tissue_or_cell_type
- Plasma metabolism and growth plates
- trigger_kind
- nutrient_deficiency Imported condition classification; unverified.
Boron: chemistry, nutrient interactions, low-intake studies and mechanistic uncertainties (2026-09-17) · lines 859–870
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Factorial boron/vitamin-D3 feeding experiment in chicks · source_derived_draft · unverified_draft
### boron-chick-triglycerides Boron supplementation returned elevated plasma triglyceride concentrations in vitamin-D3-inadequate chicks toward those in vitamin-D3-adequate chicks. Condition category: nutrient_deficiency nutrient_topic: Boron research collection; topical membership is not evidence of a direct dietary effect. plain_language: Some metabolic changes from inadequate vitamin D improved in this chick experiment. organism: Day-old cockerel chicks tissue_or_cell_type: Plasma metabolism and growth plates experimental_model: Factorial boron/vitamin-D3 feeding experiment in chicks limitations: Animal developmental experiment. It did not demonstrate direct CYP24A1 inhibition or that boron replaces vitamin D in humans. exposure: 26 days; basal boron ≤0.18 mg/kg with 0 or 1.4 mg/kg orthoboric acid supplement; vitamin D3 3.13 or 15.6 µg/kg evidence_span: {"source_cache": "artifacts/boron-research/8140930.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "6f8776234acbd0efd282761bbbcb0f51b39d8882c651b3f64686a890f646d4fc", "start_char": 0, "end_char": 1621, "text_sha256": "6f8776234acbd0efd282761bbbcb0f51b39d8882c651b3f64686a890f646d4fc"} [boron-p8140930] Dietary boron modifies the effects of vitamin D3 nutrition on indices of energy substrate utilization and mineral metabolism in the chick. (1994). https://pubmed.ncbi.nlm.nih.gov/8140930/ DOI: 10.1002/jbmr.5650090206
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.