Component
Plasma thiamine monophosphate concentration
Plasma thiamine monophosphate concentration
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
Baseline plasma thiamine monophosphate correlated with erythrocyte ThDP at Spearman r = 0.57 in 188 women.
Experimental context and source evidence
- availability_state
- biomarker_context Imported condition classification; unverified.
- evidence_location
- Results 3.2; Table 2
- evidence_span
- n = 188
- experimental_model
- 196 healthy rural Cambodian women aged 18-45; samples from a six-month thiamine-fortified fish-sauce intervention; plasma LC-MS/MS and erythrocyte HPLC assays.
- exposure
- Six-month thiamine-fortified fish-sauce intervention in healthy Cambodian women
- limitations
- This is a different analyte from free plasma thiamine; a moderate correlation does not make the assays interchangeable.
- nutrient_topic
- Thiamine research collection; topical membership is not evidence of a direct dietary effect. · Thiamine (vitamin B1)
- organism
- Homo sapiens
- plain_language
- The phosphorylated plasma form was also related to red-cell cofactor concentration.
- primary_references
- [mccann-2017-plasma-erythrocyte] Comparable Performance Characteristics of Plasma Thiamine and Erythrocyte Thiamine Diphosphate in Response to Thiamine Fortification in Rural Cambodian Women (2017). https://pmc.ncbi.nlm.nih.gov/articles/PMC5537791/ DOI: 10.3390/nu9070676
- tissue_or_cell_type
- Plasma and erythrocytes
- trigger_kind
- biomarker_context Imported condition classification; unverified.
Thiamine: mechanisms, deficiency and nutrient interactions (2026-09-17) · lines 1465–1477
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · 196 healthy rural Cambodian women aged 18-45; samples from a six-month thiamine-fortified fish-sauce intervention; plasma LC-MS/MS and erythrocyte HPLC assays. · source_derived_draft · unverified_draft
### thiamine-def-plasma-tmp-erythrocyte-correlation Baseline plasma thiamine monophosphate correlated with erythrocyte ThDP at Spearman r = 0.57 in 188 women. Condition category: biomarker_context nutrient_topic: Thiamine research collection; topical membership is not evidence of a direct dietary effect. plain_language: The phosphorylated plasma form was also related to red-cell cofactor concentration. organism: Homo sapiens tissue_or_cell_type: Plasma and erythrocytes experimental_model: 196 healthy rural Cambodian women aged 18-45; samples from a six-month thiamine-fortified fish-sauce intervention; plasma LC-MS/MS and erythrocyte HPLC assays. limitations: This is a different analyte from free plasma thiamine; a moderate correlation does not make the assays interchangeable. evidence_location: Results 3.2; Table 2 evidence_span: n = 188 exposure: Six-month thiamine-fortified fish-sauce intervention in healthy Cambodian women [mccann-2017-plasma-erythrocyte] Comparable Performance Characteristics of Plasma Thiamine and Erythrocyte Thiamine Diphosphate in Response to Thiamine Fortification in Rural Cambodian Women (2017). https://pmc.ncbi.nlm.nih.gov/articles/PMC5537791/ DOI: 10.3390/nu9070676
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.