Component
Phenylalanine oxidation
Independent cellular process record; interpretation is limited by each linked claim and its study context.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
In seven men receiving graded lysine intakes, indicator phenylalanine oxidation fell until a breakpoint and then remained approximately constant.
Experimental context and source evidence
- availability_state
- nutrient_deficiency Imported condition classification; unverified.
- experimental_model
- Controlled isotope feeding experiment
- limitations
- Small male sample; surrogate measure; plateau is not evidence that extra lysine beyond adequacy builds more muscle.
- organism
- Homo sapiens
- plain_language
- When lysine was limiting, less of another amino acid was retained; providing more lysine changed that metabolic readout up to a plateau.
- primary_references
- [zello1993] Dietary lysine requirement of young adult males determined by oxidation of L-[1-13C]phenylalanine (1993). https://pubmed.ncbi.nlm.nih.gov/8476044/ DOI: 10.1152/ajpendo.1993.264.4.E677
- tissue_or_cell_type
- Whole-body amino-acid metabolism
- trigger_kind
- nutrient_deficiency Imported condition classification; unverified.
L-Lysine: mechanism-first literature curation (2026-09-17) · lines 638–646
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Controlled isotope feeding experiment · source_derived_draft · unverified_draft
### lysine-intake-indicator-oxidation In seven men receiving graded lysine intakes, indicator phenylalanine oxidation fell until a breakpoint and then remained approximately constant. Plain language: When lysine was limiting, less of another amino acid was retained; providing more lysine changed that metabolic readout up to a plateau. Condition category: nutrient_deficiency organism: Homo sapiens tissue_or_cell_type: Whole-body amino-acid metabolism experimental_model: Controlled isotope feeding experiment limitations: Small male sample; surrogate measure; plateau is not evidence that extra lysine beyond adequacy builds more muscle. [zello1993] Dietary lysine requirement of young adult males determined by oxidation of L-[1-13C]phenylalanine (1993). https://pubmed.ncbi.nlm.nih.gov/8476044/ DOI: 10.1152/ajpendo.1993.264.4.E677
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.