Component

Paraquat

Paraquat. Species, exposure and limitations are retained in each linked claim.

7 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

Read recorded mechanisms Open recursive mind map

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

Where it participates (unsigned role)

  1. Nasunin partly preserved catalase activity measured in the liver mitochondrial fraction.

    Nasunin → Rat catalase / Cat source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/10380622.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69", "start_char": 0, "end_char": 1009, "text_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69"}
    experimental_model
    Dietary paraquat challenge with nasunin cofeeding
    exposure
    Paraquat-containing diet with or without nasunin; dose not specified in indexed abstract
    limitations
    Preventive cofeeding is not a human poisoning treatment. A mitochondrial-fraction catalase assay does not establish mitochondrial localization of catalase.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Rats
    plain_language
    The enzyme readout was partly maintained.
    primary_references
    [nasunin-p10380622] Protective effects of dietary nasunin on paraquat-induced oxidative stress in rats. (1999). https://pubmed.ncbi.nlm.nih.gov/10380622/ DOI: 10.1271/bbb.63.799
    tissue_or_cell_type
    Liver redox markers and whole-animal responses

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 900–911

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Dietary paraquat challenge with nasunin cofeeding · source_derived_draft · unverified_draft

    ### nasunin-paraquat-catalase Nasunin partly preserved catalase activity measured in the liver mitochondrial fraction. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: The enzyme readout was partly maintained. organism: Rats tissue_or_cell_type: Liver redox markers and whole-animal responses experimental_model: Dietary paraquat challenge with nasunin cofeeding limitations: Preventive cofeeding is not a human poisoning treatment. A mitochondrial-fraction catalase assay does not establish mitochondrial localization of catalase. exposure: Paraquat-containing diet with or without nasunin; dose not specified in indexed abstract evidence_span: {"source_cache": "artifacts/nasunin-research/10380622.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69", "start_char": 0, "end_char": 1009, "text_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69"} [nasunin-p10380622] Protective effects of dietary nasunin on paraquat-induced oxidative stress in rats. (1999). https://pubmed.ncbi.nlm.nih.gov/10380622/ DOI: 10.1271/bbb.63.799
    Complete structured claim and evidence

  2. Nasunin attenuated the paraquat-associated reduction in food intake.

    Nasunin → Rat food intake source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/10380622.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69", "start_char": 0, "end_char": 1009, "text_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69"}
    experimental_model
    Dietary paraquat challenge with nasunin cofeeding
    exposure
    Paraquat-containing diet with or without nasunin; dose not specified in indexed abstract
    limitations
    Preventive cofeeding is not a human poisoning treatment. A mitochondrial-fraction catalase assay does not establish mitochondrial localization of catalase.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Rats
    plain_language
    One whole-animal stress response was smaller.
    primary_references
    [nasunin-p10380622] Protective effects of dietary nasunin on paraquat-induced oxidative stress in rats. (1999). https://pubmed.ncbi.nlm.nih.gov/10380622/ DOI: 10.1271/bbb.63.799
    tissue_or_cell_type
    Liver redox markers and whole-animal responses

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 848–859

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Dietary paraquat challenge with nasunin cofeeding · source_derived_draft · unverified_draft

    ### nasunin-paraquat-food Nasunin attenuated the paraquat-associated reduction in food intake. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: One whole-animal stress response was smaller. organism: Rats tissue_or_cell_type: Liver redox markers and whole-animal responses experimental_model: Dietary paraquat challenge with nasunin cofeeding limitations: Preventive cofeeding is not a human poisoning treatment. A mitochondrial-fraction catalase assay does not establish mitochondrial localization of catalase. exposure: Paraquat-containing diet with or without nasunin; dose not specified in indexed abstract evidence_span: {"source_cache": "artifacts/nasunin-research/10380622.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69", "start_char": 0, "end_char": 1009, "text_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69"} [nasunin-p10380622] Protective effects of dietary nasunin on paraquat-induced oxidative stress in rats. (1999). https://pubmed.ncbi.nlm.nih.gov/10380622/ DOI: 10.1271/bbb.63.799
    Complete structured claim and evidence

  3. Nasunin attenuated the paraquat-associated rise in the atherogenic index.

    Nasunin → Rat serum atherogenic index source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/10380622.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69", "start_char": 0, "end_char": 1009, "text_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69"}
    experimental_model
    Dietary paraquat challenge with nasunin cofeeding
    exposure
    Paraquat-containing diet with or without nasunin; dose not specified in indexed abstract
    limitations
    Preventive cofeeding is not a human poisoning treatment. A mitochondrial-fraction catalase assay does not establish mitochondrial localization of catalase.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Rats
    plain_language
    A serum lipid ratio changed; atherosclerosis itself was not measured.
    primary_references
    [nasunin-p10380622] Protective effects of dietary nasunin on paraquat-induced oxidative stress in rats. (1999). https://pubmed.ncbi.nlm.nih.gov/10380622/ DOI: 10.1271/bbb.63.799
    tissue_or_cell_type
    Liver redox markers and whole-animal responses

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 926–937

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Dietary paraquat challenge with nasunin cofeeding · source_derived_draft · unverified_draft

    ### nasunin-paraquat-index Nasunin attenuated the paraquat-associated rise in the atherogenic index. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: A serum lipid ratio changed; atherosclerosis itself was not measured. organism: Rats tissue_or_cell_type: Liver redox markers and whole-animal responses experimental_model: Dietary paraquat challenge with nasunin cofeeding limitations: Preventive cofeeding is not a human poisoning treatment. A mitochondrial-fraction catalase assay does not establish mitochondrial localization of catalase. exposure: Paraquat-containing diet with or without nasunin; dose not specified in indexed abstract evidence_span: {"source_cache": "artifacts/nasunin-research/10380622.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69", "start_char": 0, "end_char": 1009, "text_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69"} [nasunin-p10380622] Protective effects of dietary nasunin on paraquat-induced oxidative stress in rats. (1999). https://pubmed.ncbi.nlm.nih.gov/10380622/ DOI: 10.1271/bbb.63.799
    Complete structured claim and evidence

  4. Nasunin attenuated the paraquat-associated increase in lung weight.

    Nasunin → Rat lung weight source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/10380622.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69", "start_char": 0, "end_char": 1009, "text_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69"}
    experimental_model
    Dietary paraquat challenge with nasunin cofeeding
    exposure
    Paraquat-containing diet with or without nasunin; dose not specified in indexed abstract
    limitations
    Preventive cofeeding is not a human poisoning treatment. A mitochondrial-fraction catalase assay does not establish mitochondrial localization of catalase.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Rats
    plain_language
    This measured organ response was reduced.
    primary_references
    [nasunin-p10380622] Protective effects of dietary nasunin on paraquat-induced oxidative stress in rats. (1999). https://pubmed.ncbi.nlm.nih.gov/10380622/ DOI: 10.1271/bbb.63.799
    tissue_or_cell_type
    Liver redox markers and whole-animal responses

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 874–885

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Dietary paraquat challenge with nasunin cofeeding · source_derived_draft · unverified_draft

    ### nasunin-paraquat-lung Nasunin attenuated the paraquat-associated increase in lung weight. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: This measured organ response was reduced. organism: Rats tissue_or_cell_type: Liver redox markers and whole-animal responses experimental_model: Dietary paraquat challenge with nasunin cofeeding limitations: Preventive cofeeding is not a human poisoning treatment. A mitochondrial-fraction catalase assay does not establish mitochondrial localization of catalase. exposure: Paraquat-containing diet with or without nasunin; dose not specified in indexed abstract evidence_span: {"source_cache": "artifacts/nasunin-research/10380622.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69", "start_char": 0, "end_char": 1009, "text_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69"} [nasunin-p10380622] Protective effects of dietary nasunin on paraquat-induced oxidative stress in rats. (1999). https://pubmed.ncbi.nlm.nih.gov/10380622/ DOI: 10.1271/bbb.63.799
    Complete structured claim and evidence

  5. Nasunin attenuated the rise in liver lipid TBARS.

    Nasunin → Rat liver lipid TBARS readout source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/10380622.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69", "start_char": 0, "end_char": 1009, "text_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69"}
    experimental_model
    Dietary paraquat challenge with nasunin cofeeding
    exposure
    Paraquat-containing diet with or without nasunin; dose not specified in indexed abstract
    limitations
    Preventive cofeeding is not a human poisoning treatment. A mitochondrial-fraction catalase assay does not establish mitochondrial localization of catalase.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Rats
    plain_language
    An oxidation-related marker decreased relative to challenge alone.
    primary_references
    [nasunin-p10380622] Protective effects of dietary nasunin on paraquat-induced oxidative stress in rats. (1999). https://pubmed.ncbi.nlm.nih.gov/10380622/ DOI: 10.1271/bbb.63.799
    tissue_or_cell_type
    Liver redox markers and whole-animal responses

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 887–898

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Dietary paraquat challenge with nasunin cofeeding · source_derived_draft · unverified_draft

    ### nasunin-paraquat-tbars Nasunin attenuated the rise in liver lipid TBARS. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: An oxidation-related marker decreased relative to challenge alone. organism: Rats tissue_or_cell_type: Liver redox markers and whole-animal responses experimental_model: Dietary paraquat challenge with nasunin cofeeding limitations: Preventive cofeeding is not a human poisoning treatment. A mitochondrial-fraction catalase assay does not establish mitochondrial localization of catalase. exposure: Paraquat-containing diet with or without nasunin; dose not specified in indexed abstract evidence_span: {"source_cache": "artifacts/nasunin-research/10380622.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69", "start_char": 0, "end_char": 1009, "text_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69"} [nasunin-p10380622] Protective effects of dietary nasunin on paraquat-induced oxidative stress in rats. (1999). https://pubmed.ncbi.nlm.nih.gov/10380622/ DOI: 10.1271/bbb.63.799
    Complete structured claim and evidence

  6. Nasunin attenuated the challenge-associated fall in liver triacylglycerol.

    Nasunin → Rat liver triacylglycerol concentration source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/10380622.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69", "start_char": 0, "end_char": 1009, "text_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69"}
    experimental_model
    Dietary paraquat challenge with nasunin cofeeding
    exposure
    Paraquat-containing diet with or without nasunin; dose not specified in indexed abstract
    limitations
    Preventive cofeeding is not a human poisoning treatment. A mitochondrial-fraction catalase assay does not establish mitochondrial localization of catalase.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Rats
    plain_language
    A hepatic lipid measurement moved toward the control condition.
    primary_references
    [nasunin-p10380622] Protective effects of dietary nasunin on paraquat-induced oxidative stress in rats. (1999). https://pubmed.ncbi.nlm.nih.gov/10380622/ DOI: 10.1271/bbb.63.799
    tissue_or_cell_type
    Liver redox markers and whole-animal responses

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 913–924

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Dietary paraquat challenge with nasunin cofeeding · source_derived_draft · unverified_draft

    ### nasunin-paraquat-triglyceride Nasunin attenuated the challenge-associated fall in liver triacylglycerol. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: A hepatic lipid measurement moved toward the control condition. organism: Rats tissue_or_cell_type: Liver redox markers and whole-animal responses experimental_model: Dietary paraquat challenge with nasunin cofeeding limitations: Preventive cofeeding is not a human poisoning treatment. A mitochondrial-fraction catalase assay does not establish mitochondrial localization of catalase. exposure: Paraquat-containing diet with or without nasunin; dose not specified in indexed abstract evidence_span: {"source_cache": "artifacts/nasunin-research/10380622.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69", "start_char": 0, "end_char": 1009, "text_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69"} [nasunin-p10380622] Protective effects of dietary nasunin on paraquat-induced oxidative stress in rats. (1999). https://pubmed.ncbi.nlm.nih.gov/10380622/ DOI: 10.1271/bbb.63.799
    Complete structured claim and evidence

  7. Nasunin attenuated the paraquat-associated reduction in body weight gain.

    Nasunin → Rat body weight gain source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/10380622.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69", "start_char": 0, "end_char": 1009, "text_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69"}
    experimental_model
    Dietary paraquat challenge with nasunin cofeeding
    exposure
    Paraquat-containing diet with or without nasunin; dose not specified in indexed abstract
    limitations
    Preventive cofeeding is not a human poisoning treatment. A mitochondrial-fraction catalase assay does not establish mitochondrial localization of catalase.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Rats
    plain_language
    Weight gain was better preserved during cofeeding.
    primary_references
    [nasunin-p10380622] Protective effects of dietary nasunin on paraquat-induced oxidative stress in rats. (1999). https://pubmed.ncbi.nlm.nih.gov/10380622/ DOI: 10.1271/bbb.63.799
    tissue_or_cell_type
    Liver redox markers and whole-animal responses

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 861–872

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Dietary paraquat challenge with nasunin cofeeding · source_derived_draft · unverified_draft

    ### nasunin-paraquat-weight Nasunin attenuated the paraquat-associated reduction in body weight gain. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: Weight gain was better preserved during cofeeding. organism: Rats tissue_or_cell_type: Liver redox markers and whole-animal responses experimental_model: Dietary paraquat challenge with nasunin cofeeding limitations: Preventive cofeeding is not a human poisoning treatment. A mitochondrial-fraction catalase assay does not establish mitochondrial localization of catalase. exposure: Paraquat-containing diet with or without nasunin; dose not specified in indexed abstract evidence_span: {"source_cache": "artifacts/nasunin-research/10380622.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69", "start_char": 0, "end_char": 1009, "text_sha256": "8100a5a5537ebfde9e6d82e3c71aeb3aed980c58b2f3ae9b27400258324d1a69"} [nasunin-p10380622] Protective effects of dietary nasunin on paraquat-induced oxidative stress in rats. (1999). https://pubmed.ncbi.nlm.nih.gov/10380622/ DOI: 10.1271/bbb.63.799
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards