Component
Ovulation
Ovulation. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Ovulation occurred in 19/22 D-chiro-inositol recipients versus 6/22 placebo recipients in the 1999 PCOS trial.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/inositol-research/10219066.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "2b70007c28cc93c6f18b457701ec8b034a3bbe888db05e85eca71d50199dc854", "start_char": 0, "end_char": 2121, "text_sha256": "2b70007c28cc93c6f18b457701ec8b034a3bbe888db05e85eca71d50199dc854"}
- experimental_model
- Randomized placebo-controlled trial
- exposure
- D-chiro-inositol 1200 mg/day for 6–8 weeks versus placebo; historical study regimen
- limitations
- Small short trial, not live-birth evidence. Within-group insulin improvement was stronger than the between-group comparison.
- nutrient_topic
- Inositol research collection; topical membership is not evidence of a direct dietary effect. · Inositol (stereoisomer family)
- organism
- Homo sapiens
- plain_language
- This small trial found more ovulation with D-chiro-inositol; it did not establish improved live birth.
- primary_references
- [ino-p10219066] Ovulatory and metabolic effects of D-chiro-inositol in the polycystic ovary syndrome. (1999). https://pubmed.ncbi.nlm.nih.gov/10219066/ DOI: 10.1056/nejm199904293401703
- tissue_or_cell_type
- 44 obese women with PCOS
Inositol: synthesis, signaling, mineral interactions and conditional deficiency (2026-09-17) · lines 1289–1300
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized placebo-controlled trial · source_derived_draft · unverified_draft
### ino-dci-trial Ovulation occurred in 19/22 D-chiro-inositol recipients versus 6/22 placebo recipients in the 1999 PCOS trial. Condition category: normal nutrient_topic: Inositol research collection; topical membership is not evidence of a direct dietary effect. plain_language: This small trial found more ovulation with D-chiro-inositol; it did not establish improved live birth. organism: Homo sapiens tissue_or_cell_type: 44 obese women with PCOS experimental_model: Randomized placebo-controlled trial limitations: Small short trial, not live-birth evidence. Within-group insulin improvement was stronger than the between-group comparison. exposure: D-chiro-inositol 1200 mg/day for 6–8 weeks versus placebo; historical study regimen evidence_span: {"source_cache": "artifacts/inositol-research/10219066.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "2b70007c28cc93c6f18b457701ec8b034a3bbe888db05e85eca71d50199dc854", "start_char": 0, "end_char": 2121, "text_sha256": "2b70007c28cc93c6f18b457701ec8b034a3bbe888db05e85eca71d50199dc854"} [ino-p10219066] Ovulatory and metabolic effects of D-chiro-inositol in the polycystic ovary syndrome. (1999). https://pubmed.ncbi.nlm.nih.gov/10219066/ DOI: 10.1056/nejm199904293401703
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.