Component
Mouse transferrin iron saturation
Mouse transferrin iron saturation. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Transferrin saturation declined with curcumin on the low-iron background.
Experimental context and source evidence
- availability_state
- nutrient_deficiency Imported condition classification; unverified.
- evidence_span
- {"source_cache": "artifacts/curcumin-research/18815282.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "37d4724833996e19b5dedff95a592acbfc5123f22cef97d14656b53a82666aa8", "start_char": 0, "end_char": 1368, "text_sha256": "37d4724833996e19b5dedff95a592acbfc5123f22cef97d14656b53a82666aa8"}
- experimental_model
- 26-week mouse feeding experiment with graded dietary iron and curcumin
- exposure
- Low-iron background with graded curcumin intake
- limitations
- Mouse dietary exposure; no universal human anemia prediction. Exact dietary concentrations should be checked in the original methods before translating dose.
- nutrient_topic
- Curcumin research collection; topical membership is not evidence of a direct dietary effect. · Curcumin
- organism
- Mus musculus
- plain_language
- Less of the blood iron carrier was loaded with iron.
- primary_references
- [curcumin-p18815282] Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator. (2009). https://pubmed.ncbi.nlm.nih.gov/18815282/ DOI: 10.1182/blood-2008-05-155952
- tissue_or_cell_type
- Blood and tissue iron
- trigger_kind
- nutrient_deficiency Imported condition classification; unverified.
Curcumin: metabolism, signaling and nutrient connections (2026-09-17) · lines 619–630
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · 26-week mouse feeding experiment with graded dietary iron and curcumin · source_derived_draft · unverified_draft
### curcumin-low-iron-tsat Transferrin saturation declined with curcumin on the low-iron background. Condition category: nutrient_deficiency nutrient_topic: Curcumin research collection; topical membership is not evidence of a direct dietary effect. plain_language: Less of the blood iron carrier was loaded with iron. organism: Mus musculus tissue_or_cell_type: Blood and tissue iron experimental_model: 26-week mouse feeding experiment with graded dietary iron and curcumin limitations: Mouse dietary exposure; no universal human anemia prediction. Exact dietary concentrations should be checked in the original methods before translating dose. exposure: Low-iron background with graded curcumin intake evidence_span: {"source_cache": "artifacts/curcumin-research/18815282.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "37d4724833996e19b5dedff95a592acbfc5123f22cef97d14656b53a82666aa8", "start_char": 0, "end_char": 1368, "text_sha256": "37d4724833996e19b5dedff95a592acbfc5123f22cef97d14656b53a82666aa8"} [curcumin-p18815282] Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator. (2009). https://pubmed.ncbi.nlm.nih.gov/18815282/ DOI: 10.1182/blood-2008-05-155952
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.