Component
Mouse intestinal pantothenate uptake
Mouse intestinal pantothenate uptake. Experimental context and limitations are specified in the linked claims.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Dietary pantothenate level did not change mouse intestinal pantothenate uptake assayed at 5 micromolar, including comparisons involving pantothenate-deficient diets.
Experimental context and source evidence
- availability_state
- nutrient_deficiency Imported condition classification; unverified.
- cross_nutrient
- false
- experimental_model
- Mice fed pantothenic-acid-deficient, normal or high-pantothenic-acid diets; intestinal uptake assays
- exposure
- High, normal and deficient pantothenate diets; uptake assayed at 5 micromolar. An antibiotic was needed to elicit severe deficiency; exact diet amounts and antibiotic are not reported in the abstract.
- limitations
- The abstract also describes a small late-deficiency increase in Vmax. A null result at 5 micromolar does not rule out all transport adaptation. Antibiotic use complicates attribution and does not quantify the human microbiome contribution.
- nutrient_topic
- Pantothenic acid (vitamin B5) research collection; topical membership is not evidence of a direct dietary effect. · Pantothenate (vitamin B5)
- organism
- Mus musculus
- plain_language
- Low dietary B5 did not cause a clear increase in intestinal B5 uptake at the tested concentration.
- primary_references
- [b5-trans-diet1989] Do dietary levels of pantothenic acid regulate its intestinal uptake in mice? (1989). https://pubmed.ncbi.nlm.nih.gov/2621490/ DOI: 10.1093/jn/119.12.1973
- tissue_or_cell_type
- Small intestine
- trigger_kind
- nutrient_deficiency Imported condition classification; unverified.
Pantothenic acid (vitamin B5): coenzyme A, deficiency and nutrient interactions (2026-09-17) · lines 262–273
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Mice fed pantothenic-acid-deficient, normal or high-pantothenic-acid diets; intestinal uptake assays · source_derived_draft · unverified_draft
### b5-trans-dietary-deficiency-uptake Dietary pantothenate level did not change mouse intestinal pantothenate uptake assayed at 5 micromolar, including comparisons involving pantothenate-deficient diets. Condition category: nutrient_deficiency nutrient_topic: Pantothenic acid (vitamin B5) research collection; topical membership is not evidence of a direct dietary effect. plain_language: Low dietary B5 did not cause a clear increase in intestinal B5 uptake at the tested concentration. organism: Mus musculus tissue_or_cell_type: Small intestine experimental_model: Mice fed pantothenic-acid-deficient, normal or high-pantothenic-acid diets; intestinal uptake assays limitations: The abstract also describes a small late-deficiency increase in Vmax. A null result at 5 micromolar does not rule out all transport adaptation. Antibiotic use complicates attribution and does not quantify the human microbiome contribution. exposure: High, normal and deficient pantothenate diets; uptake assayed at 5 micromolar. An antibiotic was needed to elicit severe deficiency; exact diet amounts and antibiotic are not reported in the abstract. cross_nutrient: false [b5-trans-diet1989] Do dietary levels of pantothenic acid regulate its intestinal uptake in mice? (1989). https://pubmed.ncbi.nlm.nih.gov/2621490/ DOI: 10.1093/jn/119.12.1973
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.