Component
Lycopene uptake by mouse adipose explants
Lycopene uptake by mouse adipose explants. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Adipose explants from Cd36-null mice took up less lycopene than wild-type explants.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/lycopene-research/21462325.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "de4990e5a9c520e6e528e181a4e81a469a4ebac313151bfa7828ad935b04a823", "start_char": 0, "end_char": 1048, "text_sha256": "de4990e5a9c520e6e528e181a4e81a469a4ebac313151bfa7828ad935b04a823"}
- experimental_model
- Transport inhibition, siRNA, overexpression and knockout explants
- exposure
- CD36 inhibitor, partial knockdown and Cd36-null tissue
- limitations
- Do not relabel adipose results as intestinal uptake or a clinical human transport-deficiency syndrome.
- nutrient_topic
- Lycopene research collection; topical membership is not evidence of a direct dietary effect. · Lycopene
- organism
- Mouse 3T3-L1 adipocytes and mouse adipose explants; COS-1 expression experiment
- plain_language
- Removing this transporter reduced entry into mouse fat tissue.
- primary_references
- [lycopene-p21462325] CD36 is involved in lycopene and lutein uptake by adipocytes and adipose tissue cultures. (2011). https://pubmed.ncbi.nlm.nih.gov/21462325/ DOI: 10.1002/mnfr.201000399
- tissue_or_cell_type
- Adipocytes and adipose tissue
Lycopene: absorption, metabolism, nutrient connections and human outcomes (2026-09-17) · lines 273–284
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Transport inhibition, siRNA, overexpression and knockout explants · source_derived_draft · unverified_draft
### lycopene-cd36-knockout Adipose explants from Cd36-null mice took up less lycopene than wild-type explants. Condition category: normal nutrient_topic: Lycopene research collection; topical membership is not evidence of a direct dietary effect. plain_language: Removing this transporter reduced entry into mouse fat tissue. organism: Mouse 3T3-L1 adipocytes and mouse adipose explants; COS-1 expression experiment tissue_or_cell_type: Adipocytes and adipose tissue experimental_model: Transport inhibition, siRNA, overexpression and knockout explants limitations: Do not relabel adipose results as intestinal uptake or a clinical human transport-deficiency syndrome. exposure: CD36 inhibitor, partial knockdown and Cd36-null tissue evidence_span: {"source_cache": "artifacts/lycopene-research/21462325.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "de4990e5a9c520e6e528e181a4e81a469a4ebac313151bfa7828ad935b04a823", "start_char": 0, "end_char": 1048, "text_sha256": "de4990e5a9c520e6e528e181a4e81a469a4ebac313151bfa7828ad935b04a823"} [lycopene-p21462325] CD36 is involved in lycopene and lutein uptake by adipocytes and adipose tissue cultures. (2011). https://pubmed.ncbi.nlm.nih.gov/21462325/ DOI: 10.1002/mnfr.201000399
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.