Component
Melatonin, magnesium and zinc study mixture
Melatonin, magnesium and zinc study mixture. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
The combination improved global PSQI sleep-quality scores compared with placebo.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/melatonin-research/21226679.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "2381a465728ea91061029d1d1d565623a15bdb941acf0cc9dbd2ed872fda32cf", "start_char": 0, "end_char": 1911, "text_sha256": "2381a465728ea91061029d1d1d565623a15bdb941acf0cc9dbd2ed872fda32cf"}
- experimental_model
- Double-blind placebo-controlled mixture trial
- exposure
- 5 mg melatonin, 225 mg magnesium and 11.25 mg zinc nightly for eight weeks
- limitations
- Three active ingredients without separate ingredient arms; cannot demonstrate synergy or identify which ingredient caused the improvement. Single facility and short duration.
- nutrient_topic
- Melatonin research collection; topical membership is not evidence of a direct dietary effect. · Melatonin
- organism
- 43 elderly long-term-care residents with primary insomnia
- plain_language
- The tested product helped this outcome, but it does not isolate magnesium, zinc or melatonin.
- primary_references
- [melatonin-p21226679] The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial. (2011). https://pubmed.ncbi.nlm.nih.gov/21226679/ DOI: 10.1111/j.1532-5415.2010.03232.x
- tissue_or_cell_type
- Subjective and device-estimated sleep
Melatonin: synthesis, receptors, circadian timing and nutrient interactions (2026-09-17) · lines 825–836
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Double-blind placebo-controlled mixture trial · source_derived_draft · unverified_draft
### melatonin-mg-zinc-mixture-sleep The combination improved global PSQI sleep-quality scores compared with placebo. Condition category: normal nutrient_topic: Melatonin research collection; topical membership is not evidence of a direct dietary effect. plain_language: The tested product helped this outcome, but it does not isolate magnesium, zinc or melatonin. organism: 43 elderly long-term-care residents with primary insomnia tissue_or_cell_type: Subjective and device-estimated sleep experimental_model: Double-blind placebo-controlled mixture trial limitations: Three active ingredients without separate ingredient arms; cannot demonstrate synergy or identify which ingredient caused the improvement. Single facility and short duration. exposure: 5 mg melatonin, 225 mg magnesium and 11.25 mg zinc nightly for eight weeks evidence_span: {"source_cache": "artifacts/melatonin-research/21226679.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "2381a465728ea91061029d1d1d565623a15bdb941acf0cc9dbd2ed872fda32cf", "start_char": 0, "end_char": 1911, "text_sha256": "2381a465728ea91061029d1d1d565623a15bdb941acf0cc9dbd2ed872fda32cf"} [melatonin-p21226679] The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial. (2011). https://pubmed.ncbi.nlm.nih.gov/21226679/ DOI: 10.1111/j.1532-5415.2010.03232.x
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.