Component
Ergothioneine uptake into isolated mammalian mitochondria
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Mass spectrometry detected ergothioneine entry into isolated mitochondria and mitochondrial presence after treating cells and animals.
Experimental context and source evidence
- evidence_access
- Primary indexed abstract; numerical exposures and tissue-specific methods not available in the abstract.
- experimental_model
- Isolated mitochondria, treated cells and animals; tissue and dose details not extracted from the abstract.
- interpretation_status
- Source-derived research curation; not independent raw-data verification.
- limitations
- Mitochondrial localisation alone does not establish disease prevention or identify the membrane transporter.
- nutrient_topic
- Ergothioneine mitochondrial supplement; shared molecular requirements are not demonstrated dietary interactions. · L-Ergothioneine
- plain_language
- Cell entry and mitochondrial entry are separate transport questions.
- primary_references
- Fong et al. Ergothioneine and mitochondria: An important protective mechanism? DOI 10.1016/j.bbrc.2024.150269; PMID 38909533; https://pubmed.ncbi.nlm.nih.gov/38909533/
- source_locator
- Abstract
Ergothioneine: mitochondrial transport, MPST and sulfur-handling dependencies (2026-10-02) · lines 25–25
Original AI-assisted curation of five primary studies with publication identifiers, experimental locators and access limitations. Additive chapter supplement, not publisher full text. · supports · Isolated mitochondria, treated cells and animals; tissue and dose details not extracted from the abstract. · source_derived_draft · unverified_draft
Mass spectrometry detected ergothioneine entry into isolated mitochondria and mitochondrial presence after treating cells and animals.
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.