Component
Intestinal PLP absorption
Apparent movement of phosphorylated PLP across intestine; model-dependent evidence.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Hydrolysis-protected rat intestinal sacs showed serosal PLP appearance; the authors interpreted accompanying venous data as supporting some direct phosphorylated-PLP absorption.
Experimental context and source evidence
- evidence_location
- Indexed abstract: hydrolysis-protected sac experiments and in-situ sampling
- experimental_model
- Rat everted intestinal sacs and mesenteric venous sampling.
- exposure
- Physiological-range 0.1-1 micromolar PLP and additional concentration-response experiments.
- limitations
- Does not establish the quantitative contribution in humans or exclude hydrolysis/rephosphorylation in every preparation.
- nutrient_topic
- Vitamin B6 research collection; topical membership is not evidence of a direct dietary effect. · Vitamin B6
- organism
- Rattus norvegicus
- plain_language
- A rat experiment suggests PLP can sometimes cross intact.
- primary_references
- [morita1988] Intestinal absorption of pyridoxal 5'-phosphate at physiological levels in rats. (1988). https://pubmed.ncbi.nlm.nih.gov/3244043/ DOI: 10.3177/jnsv.34.553
- tissue_or_cell_type
- Small intestine
Vitamin B6: mechanisms, deficiency and nutrient interactions (2026-09-17) · lines 98–109
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Rat everted intestinal sacs and mesenteric venous sampling. · source_derived_draft · unverified_draft
### b6-transport-rat-direct-plp Hydrolysis-protected rat intestinal sacs showed serosal PLP appearance; the authors interpreted accompanying venous data as supporting some direct phosphorylated-PLP absorption. Condition category: normal nutrient_topic: Vitamin B6 research collection; topical membership is not evidence of a direct dietary effect. plain_language: A rat experiment suggests PLP can sometimes cross intact. organism: Rattus norvegicus tissue_or_cell_type: Small intestine experimental_model: Rat everted intestinal sacs and mesenteric venous sampling. limitations: Does not establish the quantitative contribution in humans or exclude hydrolysis/rephosphorylation in every preparation. exposure: Physiological-range 0.1-1 micromolar PLP and additional concentration-response experiments. evidence_location: Indexed abstract: hydrolysis-protected sac experiments and in-situ sampling [morita1988] Intestinal absorption of pyridoxal 5'-phosphate at physiological levels in rats. (1988). https://pubmed.ncbi.nlm.nih.gov/3244043/ DOI: 10.3177/jnsv.34.553
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.