Component
Human intestinal permeability measured by sugar probes
Human intestinal permeability measured by sugar probes. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Measured gastroduodenal, small-intestinal, colonic and whole-gut permeability did not improve significantly.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/pectin-research/31324040.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "4794205aa64876bf788ee1195c9a68a69c3090a0d334eaf6fc2dbf201c02858e", "start_char": 0, "end_char": 1425, "text_sha256": "4794205aa64876bf788ee1195c9a68a69c3090a0d334eaf6fc2dbf201c02858e"}
- experimental_model
- Randomized controlled feeding; 52 young and 48 older adults enrolled
- exposure
- 15 g/day pectin versus placebo for four weeks
- limitations
- Same intervention cohort as PMID31547291; healthy baseline participants. A null result here does not settle disease-specific effects.
- nutrient_topic
- Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
- organism
- Homo sapiens
- plain_language
- The trial did not show improved measured gut permeability.
- primary_references
- [pectin-p31324040] The Impact of Pectin Supplementation on Intestinal Barrier Function in Healthy Young Adults and Healthy Elderly. (2019). https://pubmed.ncbi.nlm.nih.gov/31324040/ DOI: 10.3390/nu11071554
- tissue_or_cell_type
- Intestinal sugar permeability probes and colonic biopsies
Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 1023–1034
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized controlled feeding; 52 young and 48 older adults enrolled · source_derived_draft · unverified_draft
### pectin-barrier-null Measured gastroduodenal, small-intestinal, colonic and whole-gut permeability did not improve significantly. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: The trial did not show improved measured gut permeability. organism: Homo sapiens tissue_or_cell_type: Intestinal sugar permeability probes and colonic biopsies experimental_model: Randomized controlled feeding; 52 young and 48 older adults enrolled limitations: Same intervention cohort as PMID31547291; healthy baseline participants. A null result here does not settle disease-specific effects. exposure: 15 g/day pectin versus placebo for four weeks evidence_span: {"source_cache": "artifacts/pectin-research/31324040.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "4794205aa64876bf788ee1195c9a68a69c3090a0d334eaf6fc2dbf201c02858e", "start_char": 0, "end_char": 1425, "text_sha256": "4794205aa64876bf788ee1195c9a68a69c3090a0d334eaf6fc2dbf201c02858e"} [pectin-p31324040] The Impact of Pectin Supplementation on Intestinal Barrier Function in Healthy Young Adults and Healthy Elderly. (2019). https://pubmed.ncbi.nlm.nih.gov/31324040/ DOI: 10.3390/nu11071554
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.