Component
Infant cardiomyopathy
Infant cardiomyopathy
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
In the 11-child severe-case series, three of five children with cardiac involvement had cardiomyopathy and died during the acute phase.
Experimental context and source evidence
- availability_state
- nutrient_deficiency Imported condition classification; unverified.
- evidence_location
- Abstract Patients
- evidence_span
- had cardiomyopathy and died in the acute phase
- experimental_model
- Case series of 11 severely affected children from the Israeli thiamine-deficient formula outbreak, with longitudinal follow-up of eight initial survivors.
- exposure
- Consumption of a formula with thiamine below the assay detection limit
- limitations
- Selected severe cases cannot estimate risk among all formula-exposed infants or demonstrate a particular molecular cause of cardiomyopathy.
- nutrient_topic
- Thiamine research collection; topical membership is not evidence of a direct dietary effect. · Thiamine (vitamin B1)
- organism
- Homo sapiens
- plain_language
- Severe infant thiamine deficiency could involve fatal heart disease.
- primary_references
- [mimouni-bloch-2014-infant-followup] Thiamine deficiency in infancy: long-term follow-up. (2014). https://pubmed.ncbi.nlm.nih.gov/25160536/ DOI: 10.1016/j.pediatrneurol.2014.05.010
- tissue_or_cell_type
- Heart and clinical course
- trigger_kind
- nutrient_deficiency Imported condition classification; unverified.
Thiamine: mechanisms, deficiency and nutrient interactions (2026-09-17) · lines 1507–1519
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Case series of 11 severely affected children from the Israeli thiamine-deficient formula outbreak, with longitudinal follow-up of eight initial survivors. · source_derived_draft · unverified_draft
### thiamine-def-infant-acute-cardiomyopathy In the 11-child severe-case series, three of five children with cardiac involvement had cardiomyopathy and died during the acute phase. Condition category: nutrient_deficiency nutrient_topic: Thiamine research collection; topical membership is not evidence of a direct dietary effect. plain_language: Severe infant thiamine deficiency could involve fatal heart disease. organism: Homo sapiens tissue_or_cell_type: Heart and clinical course experimental_model: Case series of 11 severely affected children from the Israeli thiamine-deficient formula outbreak, with longitudinal follow-up of eight initial survivors. limitations: Selected severe cases cannot estimate risk among all formula-exposed infants or demonstrate a particular molecular cause of cardiomyopathy. evidence_location: Abstract Patients evidence_span: had cardiomyopathy and died in the acute phase exposure: Consumption of a formula with thiamine below the assay detection limit [mimouni-bloch-2014-infant-followup] Thiamine deficiency in infancy: long-term follow-up. (2014). https://pubmed.ncbi.nlm.nih.gov/25160536/ DOI: 10.1016/j.pediatrneurol.2014.05.010
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.