Component
HydroCurc formulation
HydroCurc formulation. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
HydroCurc did not impair the acute serum-iron response to either tested ferrous-iron dose.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/curcumin-research/34371810.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "c7dc5d4a48b51f1b27c4cca67fa4d5756197ee3baec9d8c1f2ccccfb5789e3e4", "start_char": 0, "end_char": 2316, "text_sha256": "c7dc5d4a48b51f1b27c4cca67fa4d5756197ee3baec9d8c1f2ccccfb5789e3e4"}
- experimental_model
- Double-blind randomized acute supplementation trial; 155 healthy participants
- exposure
- HydroCurc 500 mg with 18 or 65 mg ferrous iron versus matched iron controls
- limitations
- Serum iron appearance is an indirect absorption-related endpoint, not isotope absorption or long-term iron balance; healthy participants and one formulation.
- nutrient_topic
- Curcumin research collection; topical membership is not evidence of a direct dietary effect. · Curcumin
- organism
- Homo sapiens
- plain_language
- This human experiment did not reproduce a reduction in the measured iron response.
- primary_references
- [curcumin-p34371810] Acute Administration of Bioavailable Curcumin Alongside Ferrous Sulphate Supplements Does Not Impair Iron Absorption in Healthy Adults in a Randomised Trial. (2021). https://pubmed.ncbi.nlm.nih.gov/34371810/ DOI: 10.3390/nu13072300
- tissue_or_cell_type
- Serum iron at baseline and 180 minutes
Curcumin: metabolism, signaling and nutrient connections (2026-09-17) · lines 736–747
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Double-blind randomized acute supplementation trial; 155 healthy participants · source_derived_draft · unverified_draft
### curcumin-human-iron-null HydroCurc did not impair the acute serum-iron response to either tested ferrous-iron dose. Condition category: normal nutrient_topic: Curcumin research collection; topical membership is not evidence of a direct dietary effect. plain_language: This human experiment did not reproduce a reduction in the measured iron response. organism: Homo sapiens tissue_or_cell_type: Serum iron at baseline and 180 minutes experimental_model: Double-blind randomized acute supplementation trial; 155 healthy participants limitations: Serum iron appearance is an indirect absorption-related endpoint, not isotope absorption or long-term iron balance; healthy participants and one formulation. exposure: HydroCurc 500 mg with 18 or 65 mg ferrous iron versus matched iron controls evidence_span: {"source_cache": "artifacts/curcumin-research/34371810.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "c7dc5d4a48b51f1b27c4cca67fa4d5756197ee3baec9d8c1f2ccccfb5789e3e4", "start_char": 0, "end_char": 2316, "text_sha256": "c7dc5d4a48b51f1b27c4cca67fa4d5756197ee3baec9d8c1f2ccccfb5789e3e4"} [curcumin-p34371810] Acute Administration of Bioavailable Curcumin Alongside Ferrous Sulphate Supplements Does Not Impair Iron Absorption in Healthy Adults in a Randomised Trial. (2021). https://pubmed.ncbi.nlm.nih.gov/34371810/ DOI: 10.3390/nu13072300
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.