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(2021). https://pubmed.ncbi.nlm.nih.gov/34371810/ DOI: 10.3390/nu13072300","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Serum iron at baseline and 180 minutes","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"60568b9b-65d5-5c53-9b8d-b19eef31266a","evidence_kind":"source_excerpt","locator":"Lines 736-747","start_line":736,"end_line":747,"excerpt":"### curcumin-human-iron-null\nHydroCurc did not impair the acute serum-iron response to either tested ferrous-iron dose.\nCondition category: normal\nnutrient_topic: Curcumin research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: This human experiment did not reproduce a reduction in the measured iron response.\norganism: Homo sapiens\ntissue_or_cell_type: Serum iron at baseline and 180 minutes\nexperimental_model: Double-blind randomized acute supplementation trial; 155 healthy participants\nlimitations: Serum iron appearance is an indirect absorption-related endpoint, not isotope absorption or long-term iron balance; healthy participants and one formulation.\nexposure: HydroCurc 500 mg with 18 or 65 mg ferrous iron versus matched iron controls\nevidence_span: {\"source_cache\": \"artifacts/curcumin-research/34371810.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"c7dc5d4a48b51f1b27c4cca67fa4d5756197ee3baec9d8c1f2ccccfb5789e3e4\", \"start_char\": 0, \"end_char\": 2316, \"text_sha256\": \"c7dc5d4a48b51f1b27c4cca67fa4d5756197ee3baec9d8c1f2ccccfb5789e3e4\"}\n[curcumin-p34371810] Acute Administration of Bioavailable Curcumin Alongside Ferrous Sulphate Supplements Does Not Impair Iron Absorption in Healthy Adults in a Randomised Trial. 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