Component

Human motor-cortex intracortical facilitation

Experimental species, exposure and limitations are retained on each linked claim.

1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What acts on it

  1. Yellow-cactus-pear consumption was associated with increased motor-cortex intracortical facilitation in the preliminary human study.

    Experimental context and source evidence
    dose
    400 g yellow cactus pear fruit versus white-fruit comparator; exact indicaxanthin amount unresolved
    duration
    90 min after fruit; sessions separated by at least one week
    evidence_access
    Primary open full text, relevant results/methods and PubMed metadata.
    evidence_scope
    literature_reviewed; model-specific source-derived curation
    experimental_model
    Small healthy-male neurostimulation study
    limitations
    Whole-food single-blind preliminary study. Methods report 12 fruit/8 comparator participants and four comparator exclusions; participant accounting and fruit-color wording have inconsistencies. No isolated-compound efficacy or cognitive benefit was demonstrated.
    nutrient_topic
    Dedicated indicaxanthin chapter; original betalain family identity and shared claims preserved. · Indicaxanthin
    organism
    Small healthy-male neurostimulation study
    plain_language
    Yellow-cactus-pear consumption was associated with increased motor-cortex intracortical facilitation in the preliminary human study.
    primary_references
    Modulation of Human Motor Cortical Excitability and Plasticity by Opuntia Ficus Indica Fruit Consumption: Evidence from a Preliminary Study through Non-Invasive Brain Stimulation. (2022). https://pubmed.ncbi.nlm.nih.gov/36432601/ DOI: 10.3390/nu14224915
    route
    Oral whole fruit
    tissue
    Primary motor cortex

    Indicaxanthin: mechanisms, molecular forms and cross-actor connections (2026-09-20) · lines 261–270

    Original AI-assisted curation of thirteen additional primary studies, with twenty-six existing claims from eight studies linked unchanged. Study-specific citations and limitations retained. Not publisher full text. · supports · Small healthy-male neurostimulation study · source_derived_draft · unverified_draft

    ## indicaxanthin-human-fruit-icf Yellow-cactus-pear consumption was associated with increased motor-cortex intracortical facilitation in the preliminary human study. Model/species: Small healthy-male neurostimulation study Tissue: Primary motor cortex Exposure: 400 g yellow cactus pear fruit versus white-fruit comparator; exact indicaxanthin amount unresolved Route: Oral whole fruit Duration: 90 min after fruit; sessions separated by at least one week Limits: Whole-food single-blind preliminary study. Methods report 12 fruit/8 comparator participants and four comparator exclusions; participant accounting and fruit-color wording have inconsistencies. No isolated-compound efficacy or cognitive benefit was demonstrated. Primary reference: Modulation of Human Motor Cortical Excitability and Plasticity by Opuntia Ficus Indica Fruit Consumption: Evidence from a Preliminary Study through Non-Invasive Brain Stimulation. (2022). https://pubmed.ncbi.nlm.nih.gov/36432601/ DOI: 10.3390/nu14224915 Access: Primary open full text, relevant results/methods and PubMed metadata.
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards