Component

Lutein 10 mg plus zeaxanthin 2 mg daily combination

Lutein 10 mg plus zeaxanthin 2 mg daily combination. Species, exposure and limitations are retained in each linked claim.

8 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

Read recorded mechanisms Open recursive mind map

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What it acts on

  1. In the lowest dietary L+Z quintile, cataract-surgery HR was 0.68 (95% CI 0.48–0.96; P=0.03).

    Lutein 10 mg plus zeaxanthin 2 mg daily combination → Cataract surgery occurrence source_derived_draftungraded
    Experimental context and source evidence
    availability_state
    biomarker_context Imported condition classification; unverified.
    evidence_span
    {"source_cache": "artifacts/lutein-research/23645227.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "3e75988c75dde9e6525246ae68335c49c03c31f02c7419dcf74110966b7dce32", "start_char": 0, "end_char": 2245, "text_sha256": "3e75988c75dde9e6525246ae68335c49c03c31f02c7419dcf74110966b7dce32"}
    experimental_model
    AREDS2 cataract secondary outcome and dietary subgroup analysis
    exposure
    L+Z 10/2 mg daily; median 4.7 years
    limitations
    Lowest-intake subgroup is not a clinical deficiency diagnosis; overall and subgroup results must stay separate.
    nutrient_topic
    Lutein research collection; topical membership is not evidence of a direct dietary effect. · Lutein
    organism
    3159 participants phakic in at least one eye
    plain_language
    A subgroup with lower intake had a favorable estimate.
    primary_references
    [lutein-p23645227] Lutein/zeaxanthin for the treatment of age-related cataract: AREDS2 randomized trial report no. 4. (2013). https://pubmed.ncbi.nlm.nih.gov/23645227/ DOI: 10.1001/jamaophthalmol.2013.4412
    tissue_or_cell_type
    6027 study eyes
    trigger_kind
    biomarker_context Imported condition classification; unverified.

    Lutein: metabolism, signaling and nutrient connections (2026-09-17) · lines 827–838

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · AREDS2 cataract secondary outcome and dietary subgroup analysis · source_derived_draft · unverified_draft

    ### lutein-cataract-low-intake In the lowest dietary L+Z quintile, cataract-surgery HR was 0.68 (95% CI 0.48–0.96; P=0.03). Condition category: biomarker_context nutrient_topic: Lutein research collection; topical membership is not evidence of a direct dietary effect. plain_language: A subgroup with lower intake had a favorable estimate. organism: 3159 participants phakic in at least one eye tissue_or_cell_type: 6027 study eyes experimental_model: AREDS2 cataract secondary outcome and dietary subgroup analysis limitations: Lowest-intake subgroup is not a clinical deficiency diagnosis; overall and subgroup results must stay separate. exposure: L+Z 10/2 mg daily; median 4.7 years evidence_span: {"source_cache": "artifacts/lutein-research/23645227.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "3e75988c75dde9e6525246ae68335c49c03c31f02c7419dcf74110966b7dce32", "start_char": 0, "end_char": 2245, "text_sha256": "3e75988c75dde9e6525246ae68335c49c03c31f02c7419dcf74110966b7dce32"} [lutein-p23645227] Lutein/zeaxanthin for the treatment of age-related cataract: AREDS2 randomized trial report no. 4. (2013). https://pubmed.ncbi.nlm.nih.gov/23645227/ DOI: 10.1001/jamaophthalmol.2013.4412
    Complete structured claim and evidence

  2. Overall cataract-surgery HR was 0.96 (95% CI 0.84–1.10; P=0.54).

    Lutein 10 mg plus zeaxanthin 2 mg daily combination → Cataract surgery occurrence source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/lutein-research/23645227.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "3e75988c75dde9e6525246ae68335c49c03c31f02c7419dcf74110966b7dce32", "start_char": 0, "end_char": 2245, "text_sha256": "3e75988c75dde9e6525246ae68335c49c03c31f02c7419dcf74110966b7dce32"}
    experimental_model
    AREDS2 cataract secondary outcome and dietary subgroup analysis
    exposure
    L+Z 10/2 mg daily; median 4.7 years
    limitations
    Lowest-intake subgroup is not a clinical deficiency diagnosis; overall and subgroup results must stay separate.
    nutrient_topic
    Lutein research collection; topical membership is not evidence of a direct dietary effect. · Lutein
    organism
    3159 participants phakic in at least one eye
    plain_language
    The trial did not show an overall cataract-surgery benefit.
    primary_references
    [lutein-p23645227] Lutein/zeaxanthin for the treatment of age-related cataract: AREDS2 randomized trial report no. 4. (2013). https://pubmed.ncbi.nlm.nih.gov/23645227/ DOI: 10.1001/jamaophthalmol.2013.4412
    tissue_or_cell_type
    6027 study eyes

    Lutein: metabolism, signaling and nutrient connections (2026-09-17) · lines 814–825

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · AREDS2 cataract secondary outcome and dietary subgroup analysis · source_derived_draft · unverified_draft

    ### lutein-cataract-overall-null Overall cataract-surgery HR was 0.96 (95% CI 0.84–1.10; P=0.54). Condition category: normal nutrient_topic: Lutein research collection; topical membership is not evidence of a direct dietary effect. plain_language: The trial did not show an overall cataract-surgery benefit. organism: 3159 participants phakic in at least one eye tissue_or_cell_type: 6027 study eyes experimental_model: AREDS2 cataract secondary outcome and dietary subgroup analysis limitations: Lowest-intake subgroup is not a clinical deficiency diagnosis; overall and subgroup results must stay separate. exposure: L+Z 10/2 mg daily; median 4.7 years evidence_span: {"source_cache": "artifacts/lutein-research/23645227.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "3e75988c75dde9e6525246ae68335c49c03c31f02c7419dcf74110966b7dce32", "start_char": 0, "end_char": 2245, "text_sha256": "3e75988c75dde9e6525246ae68335c49c03c31f02c7419dcf74110966b7dce32"} [lutein-p23645227] Lutein/zeaxanthin for the treatment of age-related cataract: AREDS2 randomized trial report no. 4. (2013). https://pubmed.ncbi.nlm.nih.gov/23645227/ DOI: 10.1001/jamaophthalmol.2013.4412
    Complete structured claim and evidence

  3. L+Z produced no significant difference in yearly cognitive composite change: 0.03 (99% CI −0.14 to 0.19; P=0.66).

    Lutein 10 mg plus zeaxanthin 2 mg daily combination → AREDS2 composite cognitive function score source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/lutein-research/26305649.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "6b4498bace6ac4564fae52aef2f95e564154631bdfa1e19b02fa6878043dbe72", "start_char": 0, "end_char": 2936, "text_sha256": "6b4498bace6ac4564fae52aef2f95e564154631bdfa1e19b02fa6878043dbe72"}
    experimental_model
    AREDS2 ancillary randomized cognitive study
    exposure
    L+Z 10/2 mg daily; five-year study on background nutrient formulas
    limitations
    Cognitive outcome, not a direct brain-lutein assay; no attribution to isolated lutein.
    nutrient_topic
    Lutein research collection; topical membership is not evidence of a direct dietary effect. · Lutein
    organism
    3501 tested older participants at AMD risk
    plain_language
    The large older-adult study did not show cognitive benefit.
    primary_references
    [lutein-p26305649] Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial. (2015). https://pubmed.ncbi.nlm.nih.gov/26305649/ DOI: 10.1001/jama.2015.9677
    tissue_or_cell_type
    Telephone cognitive test battery

    Lutein: metabolism, signaling and nutrient connections (2026-09-17) · lines 892–903

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · AREDS2 ancillary randomized cognitive study · source_derived_draft · unverified_draft

    ### lutein-cognition-areds-null L+Z produced no significant difference in yearly cognitive composite change: 0.03 (99% CI −0.14 to 0.19; P=0.66). Condition category: normal nutrient_topic: Lutein research collection; topical membership is not evidence of a direct dietary effect. plain_language: The large older-adult study did not show cognitive benefit. organism: 3501 tested older participants at AMD risk tissue_or_cell_type: Telephone cognitive test battery experimental_model: AREDS2 ancillary randomized cognitive study limitations: Cognitive outcome, not a direct brain-lutein assay; no attribution to isolated lutein. exposure: L+Z 10/2 mg daily; five-year study on background nutrient formulas evidence_span: {"source_cache": "artifacts/lutein-research/26305649.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "6b4498bace6ac4564fae52aef2f95e564154631bdfa1e19b02fa6878043dbe72", "start_char": 0, "end_char": 2936, "text_sha256": "6b4498bace6ac4564fae52aef2f95e564154631bdfa1e19b02fa6878043dbe72"} [lutein-p26305649] Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial. (2015). https://pubmed.ncbi.nlm.nih.gov/26305649/ DOI: 10.1001/jama.2015.9677
    Complete structured claim and evidence

  4. L+Z improved the tested chromatic-contrast threshold versus placebo.

    Lutein 10 mg plus zeaxanthin 2 mg daily combination → Human chromatic contrast performance source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/lutein-research/25468896.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "01231d6577e7c30e79a74525772191092df003b42344095a53faf0279f138ac3", "start_char": 0, "end_char": 2007, "text_sha256": "01231d6577e7c30e79a74525772191092df003b42344095a53faf0279f138ac3"}
    experimental_model
    Randomized double-blind placebo-controlled visual-performance study
    exposure
    Lutein 10 mg + zeaxanthin 2 mg daily for one year
    limitations
    Combined intervention; improved task performance is not evidence of AMD prevention or treatment.
    nutrient_topic
    Lutein research collection; topical membership is not evidence of a direct dietary effect. · Lutein
    organism
    115 young healthy adults
    plain_language
    Participants detected the test contrast better.
    primary_references
    [lutein-p25468896] A double-blind, placebo-controlled study on the effects of lutein and zeaxanthin on photostress recovery, glare disability, and chromatic contrast. (2014). https://pubmed.ncbi.nlm.nih.gov/25468896/ DOI: 10.1167/iovs.14-15573
    tissue_or_cell_type
    Serum, macular pigment and visual tasks

    Lutein: metabolism, signaling and nutrient connections (2026-09-17) · lines 866–877

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized double-blind placebo-controlled visual-performance study · source_derived_draft · unverified_draft

    ### lutein-contrast-improvement L+Z improved the tested chromatic-contrast threshold versus placebo. Condition category: normal nutrient_topic: Lutein research collection; topical membership is not evidence of a direct dietary effect. plain_language: Participants detected the test contrast better. organism: 115 young healthy adults tissue_or_cell_type: Serum, macular pigment and visual tasks experimental_model: Randomized double-blind placebo-controlled visual-performance study limitations: Combined intervention; improved task performance is not evidence of AMD prevention or treatment. exposure: Lutein 10 mg + zeaxanthin 2 mg daily for one year evidence_span: {"source_cache": "artifacts/lutein-research/25468896.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "01231d6577e7c30e79a74525772191092df003b42344095a53faf0279f138ac3", "start_char": 0, "end_char": 2007, "text_sha256": "01231d6577e7c30e79a74525772191092df003b42344095a53faf0279f138ac3"} [lutein-p25468896] A double-blind, placebo-controlled study on the effects of lutein and zeaxanthin on photostress recovery, glare disability, and chromatic contrast. (2014). https://pubmed.ncbi.nlm.nih.gov/25468896/ DOI: 10.1167/iovs.14-15573
    Complete structured claim and evidence

  5. Glare disability did not improve significantly in the treated group despite correlation with pigment density.

    Lutein 10 mg plus zeaxanthin 2 mg daily combination → Human disability-glare performance source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/lutein-research/25468896.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "01231d6577e7c30e79a74525772191092df003b42344095a53faf0279f138ac3", "start_char": 0, "end_char": 2007, "text_sha256": "01231d6577e7c30e79a74525772191092df003b42344095a53faf0279f138ac3"}
    experimental_model
    Randomized double-blind placebo-controlled visual-performance study
    exposure
    Lutein 10 mg + zeaxanthin 2 mg daily for one year
    limitations
    Combined intervention; improved task performance is not evidence of AMD prevention or treatment.
    nutrient_topic
    Lutein research collection; topical membership is not evidence of a direct dietary effect. · Lutein
    organism
    115 young healthy adults
    plain_language
    A biomarker correlation did not guarantee a treatment effect.
    primary_references
    [lutein-p25468896] A double-blind, placebo-controlled study on the effects of lutein and zeaxanthin on photostress recovery, glare disability, and chromatic contrast. (2014). https://pubmed.ncbi.nlm.nih.gov/25468896/ DOI: 10.1167/iovs.14-15573
    tissue_or_cell_type
    Serum, macular pigment and visual tasks

    Lutein: metabolism, signaling and nutrient connections (2026-09-17) · lines 879–890

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized double-blind placebo-controlled visual-performance study · source_derived_draft · unverified_draft

    ### lutein-glare-null Glare disability did not improve significantly in the treated group despite correlation with pigment density. Condition category: normal nutrient_topic: Lutein research collection; topical membership is not evidence of a direct dietary effect. plain_language: A biomarker correlation did not guarantee a treatment effect. organism: 115 young healthy adults tissue_or_cell_type: Serum, macular pigment and visual tasks experimental_model: Randomized double-blind placebo-controlled visual-performance study limitations: Combined intervention; improved task performance is not evidence of AMD prevention or treatment. exposure: Lutein 10 mg + zeaxanthin 2 mg daily for one year evidence_span: {"source_cache": "artifacts/lutein-research/25468896.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "01231d6577e7c30e79a74525772191092df003b42344095a53faf0279f138ac3", "start_char": 0, "end_char": 2007, "text_sha256": "01231d6577e7c30e79a74525772191092df003b42344095a53faf0279f138ac3"} [lutein-p25468896] A double-blind, placebo-controlled study on the effects of lutein and zeaxanthin on photostress recovery, glare disability, and chromatic contrast. (2014). https://pubmed.ncbi.nlm.nih.gov/25468896/ DOI: 10.1167/iovs.14-15573
    Complete structured claim and evidence

  6. L+Z increased macular pigment optical density versus placebo at all measured eccentricities.

    Lutein 10 mg plus zeaxanthin 2 mg daily combination → Human macular pigment optical density source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/lutein-research/25468896.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "01231d6577e7c30e79a74525772191092df003b42344095a53faf0279f138ac3", "start_char": 0, "end_char": 2007, "text_sha256": "01231d6577e7c30e79a74525772191092df003b42344095a53faf0279f138ac3"}
    experimental_model
    Randomized double-blind placebo-controlled visual-performance study
    exposure
    Lutein 10 mg + zeaxanthin 2 mg daily for one year
    limitations
    Combined intervention; improved task performance is not evidence of AMD prevention or treatment.
    nutrient_topic
    Lutein research collection; topical membership is not evidence of a direct dietary effect. · Lutein
    organism
    115 young healthy adults
    plain_language
    More pigment was measured in the macula.
    primary_references
    [lutein-p25468896] A double-blind, placebo-controlled study on the effects of lutein and zeaxanthin on photostress recovery, glare disability, and chromatic contrast. (2014). https://pubmed.ncbi.nlm.nih.gov/25468896/ DOI: 10.1167/iovs.14-15573
    tissue_or_cell_type
    Serum, macular pigment and visual tasks

    Lutein: metabolism, signaling and nutrient connections (2026-09-17) · lines 840–851

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized double-blind placebo-controlled visual-performance study · source_derived_draft · unverified_draft

    ### lutein-mpod-increase L+Z increased macular pigment optical density versus placebo at all measured eccentricities. Condition category: normal nutrient_topic: Lutein research collection; topical membership is not evidence of a direct dietary effect. plain_language: More pigment was measured in the macula. organism: 115 young healthy adults tissue_or_cell_type: Serum, macular pigment and visual tasks experimental_model: Randomized double-blind placebo-controlled visual-performance study limitations: Combined intervention; improved task performance is not evidence of AMD prevention or treatment. exposure: Lutein 10 mg + zeaxanthin 2 mg daily for one year evidence_span: {"source_cache": "artifacts/lutein-research/25468896.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "01231d6577e7c30e79a74525772191092df003b42344095a53faf0279f138ac3", "start_char": 0, "end_char": 2007, "text_sha256": "01231d6577e7c30e79a74525772191092df003b42344095a53faf0279f138ac3"} [lutein-p25468896] A double-blind, placebo-controlled study on the effects of lutein and zeaxanthin on photostress recovery, glare disability, and chromatic contrast. (2014). https://pubmed.ncbi.nlm.nih.gov/25468896/ DOI: 10.1167/iovs.14-15573
    Complete structured claim and evidence

  7. L+Z improved photostress recovery time versus placebo.

    Lutein 10 mg plus zeaxanthin 2 mg daily combination → Human photostress recovery time source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/lutein-research/25468896.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "01231d6577e7c30e79a74525772191092df003b42344095a53faf0279f138ac3", "start_char": 0, "end_char": 2007, "text_sha256": "01231d6577e7c30e79a74525772191092df003b42344095a53faf0279f138ac3"}
    experimental_model
    Randomized double-blind placebo-controlled visual-performance study
    exposure
    Lutein 10 mg + zeaxanthin 2 mg daily for one year
    limitations
    Combined intervention; improved task performance is not evidence of AMD prevention or treatment.
    nutrient_topic
    Lutein research collection; topical membership is not evidence of a direct dietary effect. · Lutein
    organism
    115 young healthy adults
    plain_language
    Vision recovered faster after the experimental bright flash.
    primary_references
    [lutein-p25468896] A double-blind, placebo-controlled study on the effects of lutein and zeaxanthin on photostress recovery, glare disability, and chromatic contrast. (2014). https://pubmed.ncbi.nlm.nih.gov/25468896/ DOI: 10.1167/iovs.14-15573
    tissue_or_cell_type
    Serum, macular pigment and visual tasks

    Lutein: metabolism, signaling and nutrient connections (2026-09-17) · lines 853–864

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized double-blind placebo-controlled visual-performance study · source_derived_draft · unverified_draft

    ### lutein-photostress-improvement L+Z improved photostress recovery time versus placebo. Condition category: normal nutrient_topic: Lutein research collection; topical membership is not evidence of a direct dietary effect. plain_language: Vision recovered faster after the experimental bright flash. organism: 115 young healthy adults tissue_or_cell_type: Serum, macular pigment and visual tasks experimental_model: Randomized double-blind placebo-controlled visual-performance study limitations: Combined intervention; improved task performance is not evidence of AMD prevention or treatment. exposure: Lutein 10 mg + zeaxanthin 2 mg daily for one year evidence_span: {"source_cache": "artifacts/lutein-research/25468896.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "01231d6577e7c30e79a74525772191092df003b42344095a53faf0279f138ac3", "start_char": 0, "end_char": 2007, "text_sha256": "01231d6577e7c30e79a74525772191092df003b42344095a53faf0279f138ac3"} [lutein-p25468896] A double-blind, placebo-controlled study on the effects of lutein and zeaxanthin on photostress recovery, glare disability, and chromatic contrast. (2014). https://pubmed.ncbi.nlm.nih.gov/25468896/ DOI: 10.1167/iovs.14-15573
    Complete structured claim and evidence

  8. The young-adult trial reported improved visual memory associated with supplementation.

    Lutein 10 mg plus zeaxanthin 2 mg daily combination → Visual memory score in young adults source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/lutein-research/29135938.fulltext.txt", "locator": "Primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "f60146e188d1a3093c572c3f637ebd659184f72727a75b35afd265b5ef0be71b", "start_char": 21132, "end_char": 25480, "text_sha256": "02d9398a25880c0ead3b3ef0ed91d12a98f837a8c8f89c141986dd926e1010a8"}
    experimental_model
    Small randomized double-masked placebo-controlled trial with biomarker-response analyses
    exposure
    Lutein 10 mg + zeaxanthin 2 mg daily for one year
    limitations
    Small unequal groups and multiple outcomes; attention/reasoning findings depended on pigment-response analysis. MPOD does not directly measure brain tissue.
    nutrient_topic
    Lutein research collection; topical membership is not evidence of a direct dietary effect. · Lutein
    organism
    51 analyzable healthy adults aged 18–30; 37 active and 14 placebo
    plain_language
    A small study found a benefit on a specific memory task.
    primary_references
    [lutein-p29135938] Effects of a Lutein and Zeaxanthin Intervention on Cognitive Function: A Randomized, Double-Masked, Placebo-Controlled Trial of Younger Healthy Adults. (2017). https://pubmed.ncbi.nlm.nih.gov/29135938/ DOI: 10.3390/nu9111246
    tissue_or_cell_type
    Cognitive testing and retinal pigment measurement

    Lutein: metabolism, signaling and nutrient connections (2026-09-17) · lines 905–916

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Small randomized double-masked placebo-controlled trial with biomarker-response analyses · source_derived_draft · unverified_draft

    ### lutein-young-memory The young-adult trial reported improved visual memory associated with supplementation. Condition category: normal nutrient_topic: Lutein research collection; topical membership is not evidence of a direct dietary effect. plain_language: A small study found a benefit on a specific memory task. organism: 51 analyzable healthy adults aged 18–30; 37 active and 14 placebo tissue_or_cell_type: Cognitive testing and retinal pigment measurement experimental_model: Small randomized double-masked placebo-controlled trial with biomarker-response analyses limitations: Small unequal groups and multiple outcomes; attention/reasoning findings depended on pigment-response analysis. MPOD does not directly measure brain tissue. exposure: Lutein 10 mg + zeaxanthin 2 mg daily for one year evidence_span: {"source_cache": "artifacts/lutein-research/29135938.fulltext.txt", "locator": "Primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "f60146e188d1a3093c572c3f637ebd659184f72727a75b35afd265b5ef0be71b", "start_char": 21132, "end_char": 25480, "text_sha256": "02d9398a25880c0ead3b3ef0ed91d12a98f837a8c8f89c141986dd926e1010a8"} [lutein-p29135938] Effects of a Lutein and Zeaxanthin Intervention on Cognitive Function: A Randomized, Double-Masked, Placebo-Controlled Trial of Younger Healthy Adults. (2017). https://pubmed.ncbi.nlm.nih.gov/29135938/ DOI: 10.3390/nu9111246
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

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