Component
Dopamine sulfation by human liver cytosol
Measured cytosolic activity, not an isoform-selective purified SULT1A3 inhibition experiment.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Tartrazine inhibited dopamine sulfation in human liver cytosol.
Experimental context and source evidence
- dose
- Tartrazine in an additive-inhibition panel; concentration and substrate amounts not in abstract
- duration
- Assay interval not specified in accessed abstract
- evidence_access
- Primary PubMed abstract; unrecovered method details explicitly retained.
- evidence_scope
- literature_reviewed; source-specific experimental curation
- experimental_model
- Human liver cytosolic preparations
- limitations
- A functional sulfation assay does not demonstrate direct SULT1A3 binding or altered human brain dopamine. Ethinyloestradiol findings for other additives are not transferred to tartrazine.
- nutrient_topic
- Tartrazine food-colorant chapter; nutrient, drug and peptide interactions retain their models and limits. · Tartrazine
- organism
- Human liver cytosolic preparations
- plain_language
- Tartrazine inhibited dopamine sulfation in human liver cytosol.
- primary_references
- Common food additives are potent inhibitors of human liver 17 alpha-ethinyloestradiol and dopamine sulphotransferases. (1993). https://pubmed.ncbi.nlm.nih.gov/8250957/ DOI: 10.1016/0006-2952(93)90575-h
- route
- In vitro cytosolic enzyme assay
- tissue
- Dopamine sulfation
Tartrazine: mechanisms, molecular forms and cross-actor connections (2026-09-20) · lines 259–268
Original AI-assisted curation of eighteen primary studies. Study-specific citations, negative findings and limitations retained. Not publisher full text. · supports · Human liver cytosolic preparations · source_derived_draft · unverified_draft
## tartrazine-dopamine-sulfation Tartrazine inhibited dopamine sulfation in human liver cytosol. Model/species: Human liver cytosolic preparations Tissue: Dopamine sulfation Exposure: Tartrazine in an additive-inhibition panel; concentration and substrate amounts not in abstract Route: In vitro cytosolic enzyme assay Duration: Assay interval not specified in accessed abstract Limits: A functional sulfation assay does not demonstrate direct SULT1A3 binding or altered human brain dopamine. Ethinyloestradiol findings for other additives are not transferred to tartrazine. Primary reference: Common food additives are potent inhibitors of human liver 17 alpha-ethinyloestradiol and dopamine sulphotransferases. (1993). https://pubmed.ncbi.nlm.nih.gov/8250957/ DOI: 10.1016/0006-2952(93)90575-h Access: Primary PubMed abstract; unrecovered method details explicitly retained.
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.