Component
Recovery of orally administered C3G-derived isotope in human urine and breath
Recovery of orally administered C3G-derived isotope in human urine and breath. Interpret through the linked experimental species, preparation, compartment and exposure; no universal causal effect is implied.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
After 500 mg labeled C3G in eight men, urine plus breath contained 12.38% of administered label over 48 hours; this is not intact C3G recovery.
Experimental context and source evidence
- evidence_access
- Primary indexed abstract reviewed; full methods, figures, exact doses or endpoint-specific species assignments may remain unextracted.
- experimental_model
- Eight healthy men, single oral 500 mg 13C5-C3G, 48-hour sampling.
- interpretation_status
- Source-derived extraction of a fact-checked reference; access is explicit, not independent raw-data verification.
- limitations
- Interpret only within the recorded preparation, exposure and comparator. The complete source passage retains qualifications; unspecified doses/timing have not been extracted here. No clinical efficacy, nutrient deficiency or unique molecular mediation is inferred.
- plain_language
- After 500 mg labeled C3G in eight men, urine plus breath contained 12.38% of administered label over 48 hours; this is not intact C3G recovery.
- primary_references
- Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a (13)C-tracer study. | 2013 | DOI 10.3945/ajcn.112.049247 | PMID 23604435 | https://pubmed.ncbi.nlm.nih.gov/23604435/ | https://doi.org/10.3945/ajcn.112.049247
- source_locator
- Reviewed reference lines 17-17; exact primary location described in quoted passage where extracted.
Anthocyanins: detailed mechanisms of action (reviewed 4 October 2026) · lines 17–17
Original AI-assisted review of primary studies and, where relevant, official regulatory records. Access level is retained per claim. Corrections, null results and unresolved questions remain explicit. Not publisher full text or independent replication. · supports · Eight healthy men, single oral 500 mg 13C5-C3G, 48-hour sampling. · source_derived_draft · unverified_draft
**Tracer recovery is not intact-pigment bioavailability.** Eight men received 500 mg of isotopically labeled cyanidin-3-glucoside (C3G), with sampling over 48 hours. The reported 12.38 ± 1.38% relative bioavailability comprised labeled carbon recovered in urine and breath: 5.37 ± 0.67% and 6.91 ± 1.59%, respectively. It is not 12.38% intact C3G, nor 12.38% pharmacologically active material. Combined labeled serum metabolites peaked at approximately 5.97 µM around 10.25 hours. Low urinary recovery of unchanged pigment cannot quantify total absorption. [Czank et al., 2013](https://pubmed.ncbi.nlm.nih.gov/23604435/).
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.