Component
High-fat meal with lutein esters in the 2000 crossover study
High-fat meal with lutein esters in the 2000 crossover study. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
Lutein rose 207% with the high-fat spread versus 88% with the low-fat spread during lutein-ester supplementation.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/lutein-research/10799382.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "68c85cb7c391b6bffddcdc9ca0620c8db353400604353ce62873fe74501a0868", "start_char": 0, "end_char": 1602, "text_sha256": "68c85cb7c391b6bffddcdc9ca0620c8db353400604353ce62873fe74501a0868"}
- experimental_model
- Random-sequence crossover supplementation
- exposure
- Lutein esters providing 8 mg lutein; 3 versus 36 g meal fat; seven-day periods
- limitations
- Formulation-specific short-term response; not a universal minimum fat requirement.
- nutrient_topic
- Lutein research collection; topical membership is not evidence of a direct dietary effect. · Lutein
- organism
- Human volunteers in four groups of 14–15
- plain_language
- Meal fat changed uptake from this ester formulation.
- primary_references
- [lutein-p10799382] Amount of fat in the diet affects bioavailability of lutein esters but not of alpha-carotene, beta-carotene, and vitamin E in humans. (2000). https://pubmed.ncbi.nlm.nih.gov/10799382/ DOI: 10.1093/ajcn/71.5.1187
- tissue_or_cell_type
- Plasma carotenoid response
Lutein: metabolism, signaling and nutrient connections (2026-09-17) · lines 580–591
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Random-sequence crossover supplementation · source_derived_draft · unverified_draft
### lutein-dietary-fat Lutein rose 207% with the high-fat spread versus 88% with the low-fat spread during lutein-ester supplementation. Condition category: normal nutrient_topic: Lutein research collection; topical membership is not evidence of a direct dietary effect. plain_language: Meal fat changed uptake from this ester formulation. organism: Human volunteers in four groups of 14–15 tissue_or_cell_type: Plasma carotenoid response experimental_model: Random-sequence crossover supplementation limitations: Formulation-specific short-term response; not a universal minimum fat requirement. exposure: Lutein esters providing 8 mg lutein; 3 versus 36 g meal fat; seven-day periods evidence_span: {"source_cache": "artifacts/lutein-research/10799382.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "68c85cb7c391b6bffddcdc9ca0620c8db353400604353ce62873fe74501a0868", "start_char": 0, "end_char": 1602, "text_sha256": "68c85cb7c391b6bffddcdc9ca0620c8db353400604353ce62873fe74501a0868"} [lutein-p10799382] Amount of fat in the diet affects bioavailability of lutein esters but not of alpha-carotene, beta-carotene, and vitamin E in humans. (2000). https://pubmed.ncbi.nlm.nih.gov/10799382/ DOI: 10.1093/ajcn/71.5.1187
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.