Component
Human hepatic inorganic phosphate measured by phosphorus MRS
Species, exposure, manipulation and evidence limits are specified on each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
The intravenous fructose bolus acutely lowered hepatic inorganic phosphate as sugar phosphates accumulated.
Experimental context and source evidence
- dose
- Fructose 250 mg/kg bolus
- duration
- Early 5 min changes; sugar-phosphate recovery within about 20 min
- evidence_access
- Primary abstract/metadata; unrecovered methods explicitly retained.
- evidence_scope
- literature_reviewed; source-specific curation
- experimental_model
- Seven healthy human volunteers
- exposure_scope
- Isolated fructose, intravenous
- limitations
- Injection bypasses the intestine. Magnitude cannot be assigned to a normal oral HFCS serving or to dietary phosphate deficiency.
- nutrient_topic
- HFCS chapter: actual formulation studies, component biochemistry and interventions are explicitly distinguished. · High-Fructose Corn Syrup / HFCS
- organism
- Seven healthy human volunteers
- plain_language
- The intravenous fructose bolus acutely lowered hepatic inorganic phosphate as sugar phosphates accumulated.
- primary_references
- Assessment of human liver metabolism by phosphorus-31 magnetic resonance spectroscopy. (1986). https://pubmed.ncbi.nlm.nih.gov/3730768/ DOI: 10.1259/0007-1285-59-703-695
- route
- Intravenous injection
- tissue
- Liver phosphorus-31 MRS
High-Fructose Corn Syrup: mechanism of action and metabolic impact (2026-09-20) · lines 245–255
Original AI-assisted curation of twenty primary studies and official FDA composition information, with one reused canonical glucose-transport claim. Study-specific citations, negative findings and limitations retained. Not publisher full text. · supports · Seven healthy human volunteers · source_derived_draft · unverified_draft
## hfcs-iv-phosphate The intravenous fructose bolus acutely lowered hepatic inorganic phosphate as sugar phosphates accumulated. Model/species: Seven healthy human volunteers Tissue: Liver phosphorus-31 MRS Exposure: Fructose 250 mg/kg bolus Route: Intravenous injection Duration: Early 5 min changes; sugar-phosphate recovery within about 20 min Exposure scope: Isolated fructose, intravenous Limits: Injection bypasses the intestine. Magnitude cannot be assigned to a normal oral HFCS serving or to dietary phosphate deficiency. Reference: Assessment of human liver metabolism by phosphorus-31 magnetic resonance spectroscopy. (1986). https://pubmed.ncbi.nlm.nih.gov/3730768/ DOI: 10.1259/0007-1285-59-703-695 Access: Primary abstract/metadata; unrecovered methods explicitly retained.
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.