Component

Performance after partial sleep restriction in the glycine study

Context-specific entity; species, compartment and exposure are stated on each claim.

1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What acts on it

  1. In a randomized single-blind crossover study analyzing seven healthy men after partial sleep restriction, 3 g bedtime glycine improved reported fatigue and psychomotor vigilance measures.

    Experimental context and source evidence
    evidence_access
    Primary full text
    experimental_model
    Ten male company employees enrolled, seven analyzed; 25% sleep restriction for three nights, glycine or placebo 30 minutes before bed.
    limitations
    Small selected sample, short duration and industry setting limit generalization; rat SCN experiments do not prove the human mechanism.
    nutrient_topic
    Glycine collection; species, compartment, exposure, co-substrates and manipulation remain explicit. · Glycine
    plain_language
    A small human experiment measured next-day performance rather than proving a molecular pathway.
    primary_references
    The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. · 2012 · https://pubmed.ncbi.nlm.nih.gov/22529837/ · DOI 10.3389/fneur.2012.00061

    Glycine: supply, one-carbon allocation, receptors and cross-nutrient mechanisms (2026-09-19) · lines 426–432

    AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text. · supports · Ten male company employees enrolled, seven analyzed; 25% sleep restriction for three nights, glycine or placebo 30 minutes before bed. · source_derived_draft · unverified_draft

    ## glycine-sleep-human-outcomes A small human experiment measured next-day performance rather than proving a molecular pathway. In a randomized single-blind crossover study analyzing seven healthy men after partial sleep restriction, 3 g bedtime glycine improved reported fatigue and psychomotor vigilance measures. Model: Ten male company employees enrolled, seven analyzed; 25% sleep restriction for three nights, glycine or placebo 30 minutes before bed. Limitations: Small selected sample, short duration and industry setting limit generalization; rat SCN experiments do not prove the human mechanism. Evidence access: Primary full text The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. · 2012 · https://pubmed.ncbi.nlm.nih.gov/22529837/ · DOI 10.3389/fneur.2012.00061
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards