Component
HDL3-associated LCAT activity
HDL3-associated LCAT activity. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
The lycopene-supplement arm increased HDL3-associated LCAT activity.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/lycopene-research/35978954.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "ed024b652760ea2f5ab124162690901b3e88995ea9648bea05b59f240de08c3a", "start_char": 0, "end_char": 2778, "text_sha256": "ed024b652760ea2f5ab124162690901b3e88995ea9648bea05b59f240de08c3a"}
- experimental_model
- Randomized diet/supplement trial biomarker analysis
- exposure
- Low tomato control; 224-350 mg/week food lycopene; or 70 mg/week supplement
- limitations
- Food and supplement doses differ; enzyme activities and particle sizes are surrogate endpoints, not proof of fewer events.
- nutrient_topic
- Lycopene research collection; topical membership is not evidence of a direct dietary effect. · Lycopene
- organism
- Human, 225 adults aged 40-65 years
- plain_language
- A cholesterol-handling enzyme changed in this fraction.
- primary_references
- [lycopene-p35978954] Lycopene-rich diets modulate HDL functionality and associated inflammatory markers without affecting lipoprotein size and distribution in moderately overweight, disease-free, middle-aged adults: A randomized controlled trial. (2022). https://pubmed.ncbi.nlm.nih.gov/35978954/ DOI: 10.3389/fnut.2022.954593
- tissue_or_cell_type
- HDL fractions and plasma lipoproteins
Lycopene: absorption, metabolism, nutrient connections and human outcomes (2026-09-17) · lines 1027–1038
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized diet/supplement trial biomarker analysis · source_derived_draft · unverified_draft
### lycopene-hdl-lcat The lycopene-supplement arm increased HDL3-associated LCAT activity. Condition category: normal nutrient_topic: Lycopene research collection; topical membership is not evidence of a direct dietary effect. plain_language: A cholesterol-handling enzyme changed in this fraction. organism: Human, 225 adults aged 40-65 years tissue_or_cell_type: HDL fractions and plasma lipoproteins experimental_model: Randomized diet/supplement trial biomarker analysis limitations: Food and supplement doses differ; enzyme activities and particle sizes are surrogate endpoints, not proof of fewer events. exposure: Low tomato control; 224-350 mg/week food lycopene; or 70 mg/week supplement evidence_span: {"source_cache": "artifacts/lycopene-research/35978954.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "ed024b652760ea2f5ab124162690901b3e88995ea9648bea05b59f240de08c3a", "start_char": 0, "end_char": 2778, "text_sha256": "ed024b652760ea2f5ab124162690901b3e88995ea9648bea05b59f240de08c3a"} [lycopene-p35978954] Lycopene-rich diets modulate HDL functionality and associated inflammatory markers without affecting lipoprotein size and distribution in moderately overweight, disease-free, middle-aged adults: A randomized controlled trial. (2022). https://pubmed.ncbi.nlm.nih.gov/35978954/ DOI: 10.3389/fnut.2022.954593
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.