Component
Guinea-pig liver carnitine concentration
Hepatic carnitine concentration; influenced by synthesis, transport, intake and excretion.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Hepatic carnitine was 148 +/- 9.8 nmol/g in vitamin-C-deficient guinea pigs versus 249 +/- 16.1 in controls; pair-fed animals measured 181 +/- 14.1 nmol/g (means +/- SEM).
Experimental context and source evidence
- availability_state
- nutrient_deficiency Imported condition classification; unverified.
- cross_nutrient
- Vitamin C chemistry in collagen, modified-lysine/carnitine metabolism or copper-dependent peptide/catecholamine processing.
- experimental_model
- Guinea-pig vitamin C deficiency and pair-fed comparison
- exposure
- Vitamin C deficient, control and underfed pair-fed groups; duration not verified in abstract.
- limitations
- Do not infer that every between-group comparison was statistically significant from these means; biosynthesis was not directly measured.
- nutrient_topic
- Vitamin C research collection; topical membership is not evidence of a direct dietary effect. · Vitamin C
- organism
- Cavia porcellus
- plain_language
- Both vitamin C shortage and reduced food intake affected liver carnitine in this experiment.
- primary_references
- [carnitine1983] Combined effect of ascorbic acid deficiency and underfeeding on the hepatic carnitine level in guinea-pigs. (1983). https://pubmed.ncbi.nlm.nih.gov/6852178/ DOI: 10.1007/bf01965181
- tissue_or_cell_type
- Liver
- trigger_kind
- nutrient_deficiency Imported condition classification; unverified.
Vitamin C: mechanisms, deficiency and nutrient interactions (2026-09-17) · lines 741–752
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Guinea-pig vitamin C deficiency and pair-fed comparison · source_derived_draft · unverified_draft
### vc-enzyme-deficient-liver-carnitine Hepatic carnitine was 148 +/- 9.8 nmol/g in vitamin-C-deficient guinea pigs versus 249 +/- 16.1 in controls; pair-fed animals measured 181 +/- 14.1 nmol/g (means +/- SEM). Condition category: nutrient_deficiency nutrient_topic: Vitamin C research collection; topical membership is not evidence of a direct dietary effect. plain_language: Both vitamin C shortage and reduced food intake affected liver carnitine in this experiment. organism: Cavia porcellus tissue_or_cell_type: Liver experimental_model: Guinea-pig vitamin C deficiency and pair-fed comparison limitations: Do not infer that every between-group comparison was statistically significant from these means; biosynthesis was not directly measured. cross_nutrient: Vitamin C chemistry in collagen, modified-lysine/carnitine metabolism or copper-dependent peptide/catecholamine processing. exposure: Vitamin C deficient, control and underfed pair-fed groups; duration not verified in abstract. [carnitine1983] Combined effect of ascorbic acid deficiency and underfeeding on the hepatic carnitine level in guinea-pigs. (1983). https://pubmed.ncbi.nlm.nih.gov/6852178/ DOI: 10.1007/bf01965181
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.