Component

Dimethylsilanediol

Context-specific entity; species, compartment and exposure are stated on each claim.

1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What it acts on

  1. Dimethylsilanediol had no discernible survival effect up to 50 micromolar and increased survival at higher tested doses.

    Dimethylsilanediol → Human Saos-2 colony survival source_derived_draftungraded
    Experimental context and source evidence
    evidence_access
    Primary abstract
    experimental_model
    Human osteoblast-like cell comparison.
    limitations
    Environmental silicone degradation product, not evidence that silicone polymers or supplements share this activity.
    nutrient_topic
    Silica collection; molecular form, preparation, species, exposure and manipulation remain explicit. · Silica and soluble silicon
    plain_language
    An organosilicon compound produced a different cellular response.
    primary_references
    Divergent effects of orthosilicic acid and dimethylsilanediol on cell survival and adhesion in human osteoblast-like cells. · 2008 · https://pubmed.ncbi.nlm.nih.gov/18755397/ · DOI 10.1016/j.jtemb.2008.02.001

    Silica: soluble silicon, cellular transport and particle-specific mechanisms (2026-09-19) · lines 208–214

    AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text. · supports · Human osteoblast-like cell comparison. · source_derived_draft · unverified_draft

    ## silica-dimethyl-form An organosilicon compound produced a different cellular response. Dimethylsilanediol had no discernible survival effect up to 50 micromolar and increased survival at higher tested doses. Model: Human osteoblast-like cell comparison. Limitations: Environmental silicone degradation product, not evidence that silicone polymers or supplements share this activity. Evidence access: Primary abstract Divergent effects of orthosilicic acid and dimethylsilanediol on cell survival and adhesion in human osteoblast-like cells. · 2008 · https://pubmed.ncbi.nlm.nih.gov/18755397/ · DOI 10.1016/j.jtemb.2008.02.001
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards