Component

Diallyl disulfide / DADS

Diallyl disulfide / DADS. Interpret through the linked study species, preparation, exposure and measured endpoint.

1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What it acts on

  1. Purified DADS released only a small amount of sulfide slowly with GSH; DATS impurity can explain apparent rapid DADS release.

    Experimental context and source evidence
    evidence_access
    Primary indexed abstract reviewed; full methods, exact concentrations or species-specific attribution remain unextracted unless explicitly stated in the abstract or separately verified publisher text.
    experimental_model
    Purified-compound comparison; source-specific purity interpretation.
    interpretation_status
    Source-derived extraction of a fact-checked reference; access is explicit, not independent raw-data verification.
    limitations
    Slow/minute is not zero. Historical observations remain preserved with purity qualification, not erased as fictional experiments.
    plain_language
    Purified DADS released only a small amount of sulfide slowly with GSH; DATS impurity can explain apparent rapid DADS release.
    primary_references
    Diallyl Trisulfide Is a Fast H2S Donor, but Diallyl Disulfide Is a Slow One: The Reaction Pathways and Intermediates of Glutathione with Polysulfides. | 2015 | DOI 10.1021/acs.orglett.5b01962 | PMID 26301500 | https://pubmed.ncbi.nlm.nih.gov/26301500/ | https://doi.org/10.1021/acs.orglett.5b01962
    source_locator
    Reviewed reference lines 83-83; exact primary location described in quoted passage where extracted.

    Allicin: detailed mechanisms of action (reviewed 5 October 2026) · lines 83–83

    Original AI-assisted review of primary studies and, where relevant, official regulatory records. Access level is retained per claim. Corrections, null results and unresolved questions remain explicit. Not publisher full text or independent replication. · supports · Purified-compound comparison; source-specific purity interpretation. · Recorded from source · Recorded from source

    **DATS and DADS differ.** A later chemical study found rapid GSH-dependent sulfide release from DATS, involving an allyl-perthiol intermediate, but very little and slow release from DADS. DATS contamination could account for fast release attributed to DADS. Sulfur-chain length, purity, and reaction conditions belong in the record. This qualifies older attribution without deleting either observation; it does not establish that allicin or aged garlic extract has the same behavior. [Liang 2015](https://pubmed.ncbi.nlm.nih.gov/26301500/)
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.