Component
Progression to type 2 diabetes in the specified trial
Progression to type 2 diabetes in the specified trial. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Diabetes was diagnosed in 16.4% of placebo participants and none in the extract group during the nine-month trial.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/curcumin-research/22773702.fulltext.txt", "locator": "Primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "d2f1991f0e993327d17999b977037bc985b6363b19cac0819f626ff39fc20b2c", "start_char": 2610, "end_char": 16568, "text_sha256": "1cb18c4ac70a894bf05fa5f70d42ba42348292e3b13d1e9e3d33c503d143bd98"}
- experimental_model
- Randomized double-blind placebo-controlled trial in 240 adults with prediabetes
- exposure
- Curcuminoid extract for nine months; 1500 mg/day curcuminoids in the full methods
- limitations
- Single trial in a selected population; no general guarantee of prevention or identified molecular mediator. This is an extract, not a purified-compound experiment.
- nutrient_topic
- Curcumin research collection; topical membership is not evidence of a direct dietary effect. · Curcumin
- organism
- Homo sapiens
- plain_language
- This trial found fewer new diabetes diagnoses in its treatment group.
- primary_references
- [curcumin-p22773702] Curcumin extract for prevention of type 2 diabetes. (2012). https://pubmed.ncbi.nlm.nih.gov/22773702/ DOI: 10.2337/dc12-0116
- tissue_or_cell_type
- Progression to diabetes and metabolic markers
Curcumin: metabolism, signaling and nutrient connections (2026-09-17) · lines 1022–1033
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized double-blind placebo-controlled trial in 240 adults with prediabetes · source_derived_draft · unverified_draft
### curcumin-diabetes-trial Diabetes was diagnosed in 16.4% of placebo participants and none in the extract group during the nine-month trial. Condition category: normal nutrient_topic: Curcumin research collection; topical membership is not evidence of a direct dietary effect. plain_language: This trial found fewer new diabetes diagnoses in its treatment group. organism: Homo sapiens tissue_or_cell_type: Progression to diabetes and metabolic markers experimental_model: Randomized double-blind placebo-controlled trial in 240 adults with prediabetes limitations: Single trial in a selected population; no general guarantee of prevention or identified molecular mediator. This is an extract, not a purified-compound experiment. exposure: Curcuminoid extract for nine months; 1500 mg/day curcuminoids in the full methods evidence_span: {"source_cache": "artifacts/curcumin-research/22773702.fulltext.txt", "locator": "Primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "d2f1991f0e993327d17999b977037bc985b6363b19cac0819f626ff39fc20b2c", "start_char": 2610, "end_char": 16568, "text_sha256": "1cb18c4ac70a894bf05fa5f70d42ba42348292e3b13d1e9e3d33c503d143bd98"} [curcumin-p22773702] Curcumin extract for prevention of type 2 diabetes. (2012). https://pubmed.ncbi.nlm.nih.gov/22773702/ DOI: 10.2337/dc12-0116
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.