Component
Measured D-chiro-inositol pool
Measured D-chiro-inositol pool. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
DCI in mouse plasma, stool and urine fell to very low levels on the pinitol/DCI-depleted diet, whereas levels remained stable on standard chow.
Experimental context and source evidence
- availability_state
- nutrient_deficiency Imported condition classification; unverified.
- evidence_span
- {"source_cache": "artifacts/inositol-research/19586572.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "7c6e57e631fef5921afd04f75718024d5b14ca525460e2c96275a4fc320c3b26", "start_char": 0, "end_char": 1544, "text_sha256": "7c6e57e631fef5921afd04f75718024d5b14ca525460e2c96275a4fc320c3b26"}
- experimental_model
- Dietary balance, GC-MS and stable-isotope tracing
- exposure
- Defined diets, heavy water and deuterated myo-inositol/DCI
- limitations
- Failure to detect conversion in mice does not exclude all human or isolated-tissue activity. Isotope strategy, chemical identification, species and dietary DCI contamination may contribute to disagreement with earlier radiotracer reports.
- nutrient_topic
- Inositol research collection; topical membership is not evidence of a direct dietary effect. · Inositol (stereoisomer family)
- organism
- Rats and mice; conversion tracing in mice
- plain_language
- The measured pool depended strongly on dietary input in this experiment.
- primary_references
- [ino-p19586572] d- chiro-Inositol is absorbed but not synthesised in rodents. (2009). https://pubmed.ncbi.nlm.nih.gov/19586572/ DOI: 10.1017/s0007114509990456
- tissue_or_cell_type
- Gastrointestinal absorption, plasma and excreta
- trigger_kind
- nutrient_deficiency Imported condition classification; unverified.
Inositol: synthesis, signaling, mineral interactions and conditional deficiency (2026-09-17) · lines 1250–1261
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Dietary balance, GC-MS and stable-isotope tracing · source_derived_draft · unverified_draft
### ino-dci-diet-depletion DCI in mouse plasma, stool and urine fell to very low levels on the pinitol/DCI-depleted diet, whereas levels remained stable on standard chow. Condition category: nutrient_deficiency nutrient_topic: Inositol research collection; topical membership is not evidence of a direct dietary effect. plain_language: The measured pool depended strongly on dietary input in this experiment. organism: Rats and mice; conversion tracing in mice tissue_or_cell_type: Gastrointestinal absorption, plasma and excreta experimental_model: Dietary balance, GC-MS and stable-isotope tracing limitations: Failure to detect conversion in mice does not exclude all human or isolated-tissue activity. Isotope strategy, chemical identification, species and dietary DCI contamination may contribute to disagreement with earlier radiotracer reports. exposure: Defined diets, heavy water and deuterated myo-inositol/DCI evidence_span: {"source_cache": "artifacts/inositol-research/19586572.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "7c6e57e631fef5921afd04f75718024d5b14ca525460e2c96275a4fc320c3b26", "start_char": 0, "end_char": 1544, "text_sha256": "7c6e57e631fef5921afd04f75718024d5b14ca525460e2c96275a4fc320c3b26"} [ino-p19586572] d- chiro-Inositol is absorbed but not synthesised in rodents. (2009). https://pubmed.ncbi.nlm.nih.gov/19586572/ DOI: 10.1017/s0007114509990456
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.