Component

Circulating progesterone concentration

Circulating progesterone concentration. Species, exposure and limitations are retained in each linked claim.

1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What acts on it

  1. Boron supplementation decreased serum progesterone when dietary magnesium was low in the 2004 study.

    Boron → Circulating progesterone concentration source_derived_draftungraded
    Experimental context and source evidence
    availability_state
    nutrient_deficiency Imported condition classification; unverified.
    evidence_span
    {"source_cache": "artifacts/boron-research/15724868.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "7009311021e781ba9b1e9a9244c081cf20700511cc8704e8294b1a2c55dc0e24", "start_char": 0, "end_char": 2138, "text_sha256": "7009311021e781ba9b1e9a9244c081cf20700511cc8704e8294b1a2c55dc0e24"}
    experimental_model
    Double-blind Latin-square metabolic-unit feeding in 13 postmenopausal women
    exposure
    Approximately 118 versus 318 mg Mg/day and 0.25 versus 3.25 mg B/day; 42-day periods
    limitations
    Boron had no obvious overall effect on the response to magnesium deprivation. Results cannot establish boron as a treatment for hypomagnesemia or a substitute for magnesium.
    nutrient_topic
    Boron research collection; topical membership is not evidence of a direct dietary effect. · Boron
    organism
    Human
    plain_language
    Under this low-magnesium regimen the hormone response went downward.
    primary_references
    [boron-p15724868] The alteration of magnesium, calcium and phosphorus metabolism by dietary magnesium deprivation in postmenopausal women is not affected by dietary boron deprivation. (2004). https://pubmed.ncbi.nlm.nih.gov/15724868/
    tissue_or_cell_type
    Mineral balance and endocrine measurements
    trigger_kind
    nutrient_deficiency Imported condition classification; unverified.

    Boron: chemistry, nutrient interactions, low-intake studies and mechanistic uncertainties (2026-09-17) · lines 768–779

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Double-blind Latin-square metabolic-unit feeding in 13 postmenopausal women · source_derived_draft · unverified_draft

    ### boron-progesterone-low-mg-2004 Boron supplementation decreased serum progesterone when dietary magnesium was low in the 2004 study. Condition category: nutrient_deficiency nutrient_topic: Boron research collection; topical membership is not evidence of a direct dietary effect. plain_language: Under this low-magnesium regimen the hormone response went downward. organism: Human tissue_or_cell_type: Mineral balance and endocrine measurements experimental_model: Double-blind Latin-square metabolic-unit feeding in 13 postmenopausal women limitations: Boron had no obvious overall effect on the response to magnesium deprivation. Results cannot establish boron as a treatment for hypomagnesemia or a substitute for magnesium. exposure: Approximately 118 versus 318 mg Mg/day and 0.25 versus 3.25 mg B/day; 42-day periods evidence_span: {"source_cache": "artifacts/boron-research/15724868.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "7009311021e781ba9b1e9a9244c081cf20700511cc8704e8294b1a2c55dc0e24", "start_char": 0, "end_char": 2138, "text_sha256": "7009311021e781ba9b1e9a9244c081cf20700511cc8704e8294b1a2c55dc0e24"} [boron-p15724868] The alteration of magnesium, calcium and phosphorus metabolism by dietary magnesium deprivation in postmenopausal women is not affected by dietary boron deprivation. (2004). https://pubmed.ncbi.nlm.nih.gov/15724868/
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards