Component
Calculated insulin-resistance index (formula not verified)
Calculated insulin-resistance index (formula not verified). Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
The chromium-plus-magnesium group had lower fasting glucose, fasting insulin and the reported insulin-resistance index than its own baseline; the individual-treatment groups lacked significant within-group changes.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/chromium-research/27702717.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "5a066f8a51a4f0d4b33648166fc5bae559c5132e1ae35d65347c178359447d7e", "start_char": 0, "end_char": 1556, "text_sha256": "5a066f8a51a4f0d4b33648166fc5bae559c5132e1ae35d65347c178359447d7e"}
- experimental_model
- Four-arm randomized supplementation study; 120 insulin-resistant adults
- exposure
- Three months: chromium 160 µg/day, magnesium 200 mg/day, both, or placebo
- limitations
- The abstract principally reports within-group changes, which alone do not establish a between-group interaction. T-lymphocyte mRNA is not skeletal-muscle transporter activity. Possible participant overlap with later reports is not resolved.
- nutrient_topic
- Chromium research collection; topical membership is not evidence of a direct dietary effect. · Chromium
- organism
- Human
- plain_language
- The combination showed a signal in this trial, but comparing which groups reached significance does not by itself prove synergy.
- primary_references
- [chromium-p27702717] Combined chromium and magnesium decreases insulin resistance more effectively than either alone. (2016). https://pubmed.ncbi.nlm.nih.gov/27702717/ DOI: 10.6133/apjcn.092015.48
- tissue_or_cell_type
- Blood measures and activated T lymphocytes
Chromium: transport, insulin signaling, nutrient interactions and essentiality debate (2026-09-17) · lines 562–573
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Four-arm randomized supplementation study; 120 insulin-resistant adults · source_derived_draft · unverified_draft
### chromium-magnesium-combination-2016 The chromium-plus-magnesium group had lower fasting glucose, fasting insulin and the reported insulin-resistance index than its own baseline; the individual-treatment groups lacked significant within-group changes. Condition category: normal nutrient_topic: Chromium research collection; topical membership is not evidence of a direct dietary effect. plain_language: The combination showed a signal in this trial, but comparing which groups reached significance does not by itself prove synergy. organism: Human tissue_or_cell_type: Blood measures and activated T lymphocytes experimental_model: Four-arm randomized supplementation study; 120 insulin-resistant adults limitations: The abstract principally reports within-group changes, which alone do not establish a between-group interaction. T-lymphocyte mRNA is not skeletal-muscle transporter activity. Possible participant overlap with later reports is not resolved. exposure: Three months: chromium 160 µg/day, magnesium 200 mg/day, both, or placebo evidence_span: {"source_cache": "artifacts/chromium-research/27702717.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "5a066f8a51a4f0d4b33648166fc5bae559c5132e1ae35d65347c178359447d7e", "start_char": 0, "end_char": 1556, "text_sha256": "5a066f8a51a4f0d4b33648166fc5bae559c5132e1ae35d65347c178359447d7e"} [chromium-p27702717] Combined chromium and magnesium decreases insulin resistance more effectively than either alone. (2016). https://pubmed.ncbi.nlm.nih.gov/27702717/ DOI: 10.6133/apjcn.092015.48
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.