Component
Bovine protein C / PROC
Bovine protein C / PROC. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
The tested bovine-proc Gla-domain protein showed calcium-specific contact with negatively charged phospholipid monolayers.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/k2-research/9609692.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "d29ed548c28e5a8015742351c50aa94c8853d0f1846794964b67a73324c879bd", "start_char": 0, "end_char": 2064, "text_sha256": "d29ed548c28e5a8015742351c50aa94c8853d0f1846794964b67a73324c879bd"}
- experimental_model
- Protein adsorption to model phospholipid monolayers
- exposure
- Phosphatidylserine-containing monolayers
- limitations
- Model membrane binding, not whole-blood thrombosis. Species remain distinct.
- nutrient_topic
- Vitamin K2 research collection; topical membership is not evidence of a direct dietary effect. · Vitamin K2 / menaquinone family
- organism
- Purified human and bovine proteins
- plain_language
- Carboxylation supports a protein surface that interacts with calcium and membranes.
- primary_references
- [k2-p9609692] Adsorption of vitamin K-dependent blood coagulation proteins to spread phospholipid monolayers as determined from combined measurements of the surface pressure and surface protein concentration. (1998). https://pubmed.ncbi.nlm.nih.gov/9609692/ DOI: 10.1021/bi973118+
- tissue_or_cell_type
- Calcium-dependent Gla-domain membrane contact
Vitamin K2: menaquinone forms, carboxylation, recycling and nutrient interactions (2026-09-17) · lines 981–992
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Protein adsorption to model phospholipid monolayers · source_derived_draft · unverified_draft
### k2-membrane-bovine-proc The tested bovine-proc Gla-domain protein showed calcium-specific contact with negatively charged phospholipid monolayers. Condition category: normal nutrient_topic: Vitamin K2 research collection; topical membership is not evidence of a direct dietary effect. plain_language: Carboxylation supports a protein surface that interacts with calcium and membranes. organism: Purified human and bovine proteins tissue_or_cell_type: Calcium-dependent Gla-domain membrane contact experimental_model: Protein adsorption to model phospholipid monolayers limitations: Model membrane binding, not whole-blood thrombosis. Species remain distinct. exposure: Phosphatidylserine-containing monolayers evidence_span: {"source_cache": "artifacts/k2-research/9609692.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "d29ed548c28e5a8015742351c50aa94c8853d0f1846794964b67a73324c879bd", "start_char": 0, "end_char": 2064, "text_sha256": "d29ed548c28e5a8015742351c50aa94c8853d0f1846794964b67a73324c879bd"} [k2-p9609692] Adsorption of vitamin K-dependent blood coagulation proteins to spread phospholipid monolayers as determined from combined measurements of the surface pressure and surface protein concentration. (1998). https://pubmed.ncbi.nlm.nih.gov/9609692/ DOI: 10.1021/bi973118+
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.