Component

Basal nitric-oxide-dependent vascular response

Basal nitric-oxide-dependent vascular response. Species, exposure and limitations are retained in each linked claim.

1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What acts on it

  1. Basal nitric-oxide responses were unchanged in the CVD trial arm.

    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/lycopene-research/24911964.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "d96a112b2d48544349cd136e7078ac9cdac3ecbedb41f2983db742b36e1cd8a9", "start_char": 0, "end_char": 1849, "text_sha256": "d96a112b2d48544349cd136e7078ac9cdac3ecbedb41f2983db742b36e1cd8a9"}
    experimental_model
    Double-blind placebo-controlled trial
    exposure
    7 mg lycopene daily for two months
    limitations
    Surrogate physiology, not cardiovascular events; CVD and healthy populations analyzed separately.
    nutrient_topic
    Lycopene research collection; topical membership is not evidence of a direct dietary effect. · Lycopene
    organism
    Human, 36 statin-treated CVD patients and 36 healthy volunteers
    plain_language
    Improved stimulated dilation did not establish a general rise in nitric oxide.
    primary_references
    [lycopene-p24911964] Effects of oral lycopene supplementation on vascular function in patients with cardiovascular disease and healthy volunteers: a randomised controlled trial. (2014). https://pubmed.ncbi.nlm.nih.gov/24911964/ DOI: 10.1371/journal.pone.0099070
    tissue_or_cell_type
    Forearm vascular responses

    Lycopene: absorption, metabolism, nutrient connections and human outcomes (2026-09-17) · lines 1001–1012

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Double-blind placebo-controlled trial · source_derived_draft · unverified_draft

    ### lycopene-basal-no-null Basal nitric-oxide responses were unchanged in the CVD trial arm. Condition category: normal nutrient_topic: Lycopene research collection; topical membership is not evidence of a direct dietary effect. plain_language: Improved stimulated dilation did not establish a general rise in nitric oxide. organism: Human, 36 statin-treated CVD patients and 36 healthy volunteers tissue_or_cell_type: Forearm vascular responses experimental_model: Double-blind placebo-controlled trial limitations: Surrogate physiology, not cardiovascular events; CVD and healthy populations analyzed separately. exposure: 7 mg lycopene daily for two months evidence_span: {"source_cache": "artifacts/lycopene-research/24911964.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "d96a112b2d48544349cd136e7078ac9cdac3ecbedb41f2983db742b36e1cd8a9", "start_char": 0, "end_char": 1849, "text_sha256": "d96a112b2d48544349cd136e7078ac9cdac3ecbedb41f2983db742b36e1cd8a9"} [lycopene-p24911964] Effects of oral lycopene supplementation on vascular function in patients with cardiovascular disease and healthy volunteers: a randomised controlled trial. (2014). https://pubmed.ncbi.nlm.nih.gov/24911964/ DOI: 10.1371/journal.pone.0099070
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards