Component
ADOS-2 assessment score
ADOS-2 assessment score. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
The study found no significant clinical improvement on ADOS-2, ABC or SRS-2 in the younger-child cohort.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/sulforaphane-research/36771424.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "b571349cae03a080b09b387fa132d9f534133caef7a187be028370a9db48636e", "start_char": 0, "end_char": 1410, "text_sha256": "b571349cae03a080b09b387fa132d9f534133caef7a187be028370a9db48636e"}
- experimental_model
- Prospective randomized double-blind placebo-controlled study
- exposure
- Assessments at baseline, 18 and 36 weeks
- limitations
- Small sample with attrition; different age/formulation/endpoint context is retained rather than automatically classified as a contradiction.
- nutrient_topic
- Sulforaphane research collection; topical membership is not evidence of a direct dietary effect. · Sulforaphane / SFN, stereochemistry specified per study
- organism
- Human, children aged 3-7; 40 randomized and 28 completed
- plain_language
- Later testing did not reproduce a clear benefit in this population.
- primary_references
- [sulforaphane-p36771424] Sulforaphane Treatment in Children with Autism: A Prospective Randomized Double-Blind Study. (2023). https://pubmed.ncbi.nlm.nih.gov/36771424/ DOI: 10.3390/nu15030718
- tissue_or_cell_type
- ABC, SRS-2 and ADOS-2
Sulforaphane: formation, electrophile sensing and nutrient connections (2026-09-17) · lines 1386–1397
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Prospective randomized double-blind placebo-controlled study · source_derived_draft · unverified_draft
### sulforaphane-autism-younger-null The study found no significant clinical improvement on ADOS-2, ABC or SRS-2 in the younger-child cohort. Condition category: normal nutrient_topic: Sulforaphane research collection; topical membership is not evidence of a direct dietary effect. plain_language: Later testing did not reproduce a clear benefit in this population. organism: Human, children aged 3-7; 40 randomized and 28 completed tissue_or_cell_type: ABC, SRS-2 and ADOS-2 experimental_model: Prospective randomized double-blind placebo-controlled study limitations: Small sample with attrition; different age/formulation/endpoint context is retained rather than automatically classified as a contradiction. exposure: Assessments at baseline, 18 and 36 weeks evidence_span: {"source_cache": "artifacts/sulforaphane-research/36771424.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "b571349cae03a080b09b387fa132d9f534133caef7a187be028370a9db48636e", "start_char": 0, "end_char": 1410, "text_sha256": "b571349cae03a080b09b387fa132d9f534133caef7a187be028370a9db48636e"} [sulforaphane-p36771424] Sulforaphane Treatment in Children with Autism: A Prospective Randomized Double-Blind Study. (2023). https://pubmed.ncbi.nlm.nih.gov/36771424/ DOI: 10.3390/nu15030718
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.