Component
Misclassification of former and occasional drinkers as abstainers
Misclassification of former and occasional drinkers as abstainers. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
Without adjustment the meta-analysis replicated the classic J-shaped curve with reduced mortality for low-volume drinkers (relative risk 0.86), but after adjustment for abstainer biases and study quality no significant reduction remained (relative risk 0.97), while former drinkers had elevated risk (1.22).
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/alcohol-research/26997174.abstract.txt", "locator": "Indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "db6a3810963367be7e87327becdf62060843fbd53c764a0d5c8f3d6c3084e9ec", "start_char": 0, "end_char": 2096, "text_sha256": "db6a3810963367be7e87327becdf62060843fbd53c764a0d5c8f3d6c3084e9ec"}
- experimental_model
- Systematic review and meta-regression of 87 studies, 3,998,626 people and 367,103 deaths
- exposure
- Alcohol consumption categories against all-cause mortality, adjusted for study quality
- limitations
- A bias-adjustment analysis. It does not report new participants; it reanalyses the existing cohorts after correcting how abstainers were defined.
- nutrient_topic
- Alcohol research collection; topical membership is not evidence of a direct clinical effect, and ethanol is recorded separately from the acetaldehyde it becomes. · Ethanol
- organism
- Human
- plain_language
- The apparent benefit of light drinking disappears once sick ex-drinkers are taken out of the comparison group.
- primary_references
- [alcohol-p26997174] Do "Moderate" Drinkers Have Reduced Mortality Risk? A Systematic Review and Meta-Analysis of Alcohol Consumption and All-Cause Mortality. (2016). https://pubmed.ncbi.nlm.nih.gov/26997174/ DOI: 10.15288/jsad.2016.77.185
- tissue_or_cell_type
- Whole body
Alcohol: ethanol clearance, acetaldehyde, the channels it binds, organ injury and nutrient collisions (2026-09-21) · lines 579–590
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Systematic review and meta-regression of 87 studies, 3,998,626 people and 367,103 deaths · source_derived_draft · unverified_draft
### alcohol-jcurve-artefact Without adjustment the meta-analysis replicated the classic J-shaped curve with reduced mortality for low-volume drinkers (relative risk 0.86), but after adjustment for abstainer biases and study quality no significant reduction remained (relative risk 0.97), while former drinkers had elevated risk (1.22). Condition category: normal nutrient_topic: Alcohol research collection; topical membership is not evidence of a direct clinical effect, and ethanol is recorded separately from the acetaldehyde it becomes. plain_language: The apparent benefit of light drinking disappears once sick ex-drinkers are taken out of the comparison group. organism: Human tissue_or_cell_type: Whole body experimental_model: Systematic review and meta-regression of 87 studies, 3,998,626 people and 367,103 deaths limitations: A bias-adjustment analysis. It does not report new participants; it reanalyses the existing cohorts after correcting how abstainers were defined. exposure: Alcohol consumption categories against all-cause mortality, adjusted for study quality evidence_span: {"source_cache": "artifacts/alcohol-research/26997174.abstract.txt", "locator": "Indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "db6a3810963367be7e87327becdf62060843fbd53c764a0d5c8f3d6c3084e9ec", "start_char": 0, "end_char": 2096, "text_sha256": "db6a3810963367be7e87327becdf62060843fbd53c764a0d5c8f3d6c3084e9ec"} [alcohol-p26997174] Do "Moderate" Drinkers Have Reduced Mortality Risk? A Systematic Review and Meta-Analysis of Alcohol Consumption and All-Cause Mortality. (2016). https://pubmed.ncbi.nlm.nih.gov/26997174/ DOI: 10.15288/jsad.2016.77.185
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.