Component

4′-NH2-myricetin

Context-specific entity; species, compartment and exposure are stated on each claim.

2 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What acts on it

  1. Oxidized myricetin reacted chemically with ammonia to form 4′-NH2-myricetin, structurally confirmed by NMR and LC-MS.

    Experimental context and source evidence
    evidence_access
    Primary abstract
    experimental_model
    Cell-free chemistry.
    limitations
    Not an established ammonia-detoxification therapy or enzyme-catalyzed pathway.
    nutrient_topic
    Myricetin collection; molecular form, preparation, species, exposure and manipulation remain explicit. · Myricetin
    plain_language
    Reactive nitrogen can become part of a new metabolite.
    primary_references
    Biotransformation of Myricetin: A Novel Metabolic Pathway to Produce Aminated Products in Mice. · 2019 · https://pubmed.ncbi.nlm.nih.gov/31087612/ · DOI 10.1002/mnfr.201900203

    Myricetin: metabolism, immune signaling, redox chemistry and cross-nutrient mechanisms (2026-09-19) · lines 44–50

    AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text. · supports · Cell-free chemistry. · source_derived_draft · unverified_draft

    ## myricetin-amination-chemistry Reactive nitrogen can become part of a new metabolite. Oxidized myricetin reacted chemically with ammonia to form 4′-NH2-myricetin, structurally confirmed by NMR and LC-MS. Model: Cell-free chemistry. Limitations: Not an established ammonia-detoxification therapy or enzyme-catalyzed pathway. Evidence access: Primary abstract Biotransformation of Myricetin: A Novel Metabolic Pathway to Produce Aminated Products in Mice. · 2019 · https://pubmed.ncbi.nlm.nih.gov/31087612/ · DOI 10.1002/mnfr.201900203
    Complete structured claim and evidence
  2. 4′-NH2-myricetin was identified against a synthetic standard in feces of myricetin-treated mice.

    Myricetin → 4′-NH2-myricetin source_derived_draftungraded
    Experimental context and source evidence
    evidence_access
    Primary abstract
    experimental_model
    Mouse oral-gavage metabolism study.
    limitations
    Detection does not identify the forming compartment or establish human production.
    nutrient_topic
    Myricetin collection; molecular form, preparation, species, exposure and manipulation remain explicit. · Myricetin
    plain_language
    The new molecule was also detected after dosing an animal.
    primary_references
    Biotransformation of Myricetin: A Novel Metabolic Pathway to Produce Aminated Products in Mice. · 2019 · https://pubmed.ncbi.nlm.nih.gov/31087612/ · DOI 10.1002/mnfr.201900203

    Myricetin: metabolism, immune signaling, redox chemistry and cross-nutrient mechanisms (2026-09-19) · lines 76–82

    AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text. · supports · Mouse oral-gavage metabolism study. · source_derived_draft · unverified_draft

    ## myricetin-amination-mice The new molecule was also detected after dosing an animal. 4′-NH2-myricetin was identified against a synthetic standard in feces of myricetin-treated mice. Model: Mouse oral-gavage metabolism study. Limitations: Detection does not identify the forming compartment or establish human production. Evidence access: Primary abstract Biotransformation of Myricetin: A Novel Metabolic Pathway to Produce Aminated Products in Mice. · 2019 · https://pubmed.ncbi.nlm.nih.gov/31087612/ · DOI 10.1002/mnfr.201900203
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards