Component
3,4,5-Trihydroxyphenylacetic acid
Context-specific entity; species, compartment and exposure are stated on each claim.
2 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
LC-MS analysis supported amination of 3,4,5-Trihydroxyphenylacetic acid in myricetin-treated mice.
Experimental context and source evidence
- evidence_access
- Primary abstract
- experimental_model
- Mouse fecal/plasma metabolite analysis after oral dosing.
- limitations
- Structural certainty differs from the NMR-confirmed parent amination product; no human flux measured.
- nutrient_topic
- Myricetin collection; molecular form, preparation, species, exposure and manipulation remain explicit. · Myricetin
- plain_language
- Downstream products can undergo further chemistry.
- primary_references
- Biotransformation of Myricetin: A Novel Metabolic Pathway to Produce Aminated Products in Mice. · 2019 · https://pubmed.ncbi.nlm.nih.gov/31087612/ · DOI 10.1002/mnfr.201900203
Myricetin: metabolism, immune signaling, redox chemistry and cross-nutrient mechanisms (2026-09-19) · lines 92–98
AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text. · supports · Mouse fecal/plasma metabolite analysis after oral dosing. · source_derived_draft · unverified_draft
## myricetin-acid-amination Downstream products can undergo further chemistry. LC-MS analysis supported amination of 3,4,5-Trihydroxyphenylacetic acid in myricetin-treated mice. Model: Mouse fecal/plasma metabolite analysis after oral dosing. Limitations: Structural certainty differs from the NMR-confirmed parent amination product; no human flux measured. Evidence access: Primary abstract Biotransformation of Myricetin: A Novel Metabolic Pathway to Produce Aminated Products in Mice. · 2019 · https://pubmed.ncbi.nlm.nih.gov/31087612/ · DOI 10.1002/mnfr.201900203
Complete structured claim and evidence
What acts on it
The study identified 3,4,5-trihydroxyphenylacetic acid as a microbial-derived myricetin metabolite investigated for further amination.
Experimental context and source evidence
- evidence_access
- Primary abstract
- experimental_model
- Mouse biotransformation study.
- limitations
- No specific strain, enzyme or human conversion fraction established by this record.
- nutrient_topic
- Myricetin collection; molecular form, preparation, species, exposure and manipulation remain explicit. · Myricetin
- plain_language
- Microbial breakdown produces a smaller chemical scaffold.
- primary_references
- Biotransformation of Myricetin: A Novel Metabolic Pathway to Produce Aminated Products in Mice. · 2019 · https://pubmed.ncbi.nlm.nih.gov/31087612/ · DOI 10.1002/mnfr.201900203
Myricetin: metabolism, immune signaling, redox chemistry and cross-nutrient mechanisms (2026-09-19) · lines 68–74
AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text. · supports · Mouse biotransformation study. · source_derived_draft · unverified_draft
## myricetin-ring-cleavage-product Microbial breakdown produces a smaller chemical scaffold. The study identified 3,4,5-trihydroxyphenylacetic acid as a microbial-derived myricetin metabolite investigated for further amination. Model: Mouse biotransformation study. Limitations: No specific strain, enzyme or human conversion fraction established by this record. Evidence access: Primary abstract Biotransformation of Myricetin: A Novel Metabolic Pathway to Produce Aminated Products in Mice. · 2019 · https://pubmed.ncbi.nlm.nih.gov/31087612/ · DOI 10.1002/mnfr.201900203
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.