Component
Whole-body copper retention
Whole-body copper retention. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
The study found no significant vitamin-C-period effect on copper absorption, retention, serum copper or ceruloplasmin protein despite the oxidase-activity change.
Experimental context and source evidence
- availability_state
- biomarker_context Imported condition classification; unverified.
- evidence_span
- {"source_cache": "artifacts/copper-research/3694287.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "37e70fcbc672023cd6c3616b4a1171c6ded4caafe4e3c14d4f80c6abca490e68", "start_char": 0, "end_char": 1031, "text_sha256": "37e70fcbc672023cd6c3616b4a1171c6ded4caafe4e3c14d4f80c6abca490e68"}
- experimental_model
- Controlled sequential dietary vitamin C intervention
- exposure
- Fourteen-week feeding study: 65, 5, 605 and 5 mg vitamin C/day in successive periods
- limitations
- Short sequential study; ceruloplasmin activity differs from protein concentration and whole-body copper stores. No universal vitamin C threshold is established.
- nutrient_topic
- Copper research collection; topical membership is not evidence of a direct dietary effect. · Copper
- organism
- Human men
- plain_language
- The activity change did not demonstrate loss of body copper.
- primary_references
- [copper-p3694287] Effect of varying ascorbic acid intakes on copper absorption and ceruloplasmin levels of young men. (1987). https://pubmed.ncbi.nlm.nih.gov/3694287/ DOI: 10.1093/jn/117.12.2109
- tissue_or_cell_type
- Copper absorption, retention and circulating markers
- trigger_kind
- biomarker_context Imported condition classification; unverified.
Copper: transport, cuproenzymes, deficiency, excess and nutrient interactions (2026-09-17) · lines 1118–1129
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Controlled sequential dietary vitamin C intervention · source_derived_draft · unverified_draft
### copper-ascorbate-copper-retention The study found no significant vitamin-C-period effect on copper absorption, retention, serum copper or ceruloplasmin protein despite the oxidase-activity change. Condition category: biomarker_context nutrient_topic: Copper research collection; topical membership is not evidence of a direct dietary effect. plain_language: The activity change did not demonstrate loss of body copper. organism: Human men tissue_or_cell_type: Copper absorption, retention and circulating markers experimental_model: Controlled sequential dietary vitamin C intervention limitations: Short sequential study; ceruloplasmin activity differs from protein concentration and whole-body copper stores. No universal vitamin C threshold is established. exposure: Fourteen-week feeding study: 65, 5, 605 and 5 mg vitamin C/day in successive periods evidence_span: {"source_cache": "artifacts/copper-research/3694287.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "37e70fcbc672023cd6c3616b4a1171c6ded4caafe4e3c14d4f80c6abca490e68", "start_char": 0, "end_char": 1031, "text_sha256": "37e70fcbc672023cd6c3616b4a1171c6ded4caafe4e3c14d4f80c6abca490e68"} [copper-p3694287] Effect of varying ascorbic acid intakes on copper absorption and ceruloplasmin levels of young men. (1987). https://pubmed.ncbi.nlm.nih.gov/3694287/ DOI: 10.1093/jn/117.12.2109
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.