Component

Strychnine

Strychnine. Species, exposure and limitations are retained in each linked claim.

1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

Where it participates (unsigned role)

  1. Strychnine reduced the theanine-induced dopamine response in rat striatum.

    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/theanine-research/18196445.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "59fdaf94d59c2f4b2981c29cd2981c043351aae1299a59a19e29979076957839", "start_char": 0, "end_char": 1118, "text_sha256": "59fdaf94d59c2f4b2981c29cd2981c043351aae1299a59a19e29979076957839"}
    experimental_model
    In-vivo striatal microdialysis with receptor antagonists
    exposure
    Local brain theanine administration; glycine and AMPA antagonists
    limitations
    Direct brain dosing bypasses oral absorption and blood-brain-barrier transport. Antagonist sensitivity identifies pathway involvement, not necessarily direct theanine binding.
    nutrient_topic
    L-Theanine research collection; topical membership is not evidence of a direct dietary effect. · L-Theanine
    organism
    Conscious rats
    plain_language
    The glycine-receptor pathway participated in the dopamine response.
    primary_references
    [theanine-p18196445] Theanine, gamma-glutamylethylamide, a unique amino acid in tea leaves, modulates neurotransmitter concentrations in the brain striatum interstitium in conscious rats. (2009). https://pubmed.ncbi.nlm.nih.gov/18196445/ DOI: 10.1007/s00726-007-0020-7
    tissue_or_cell_type
    Striatal extracellular neurotransmitters

    L-Theanine: metabolism, neural signaling, nutrient connections and human outcomes (2026-09-17) · lines 380–391

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · In-vivo striatal microdialysis with receptor antagonists · source_derived_draft · unverified_draft

    ### theanine-glycine-dopamine Strychnine reduced the theanine-induced dopamine response in rat striatum. Condition category: normal nutrient_topic: L-Theanine research collection; topical membership is not evidence of a direct dietary effect. plain_language: The glycine-receptor pathway participated in the dopamine response. organism: Conscious rats tissue_or_cell_type: Striatal extracellular neurotransmitters experimental_model: In-vivo striatal microdialysis with receptor antagonists limitations: Direct brain dosing bypasses oral absorption and blood-brain-barrier transport. Antagonist sensitivity identifies pathway involvement, not necessarily direct theanine binding. exposure: Local brain theanine administration; glycine and AMPA antagonists evidence_span: {"source_cache": "artifacts/theanine-research/18196445.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "59fdaf94d59c2f4b2981c29cd2981c043351aae1299a59a19e29979076957839", "start_char": 0, "end_char": 1118, "text_sha256": "59fdaf94d59c2f4b2981c29cd2981c043351aae1299a59a19e29979076957839"} [theanine-p18196445] Theanine, gamma-glutamylethylamide, a unique amino acid in tea leaves, modulates neurotransmitter concentrations in the brain striatum interstitium in conscious rats. (2009). https://pubmed.ncbi.nlm.nih.gov/18196445/ DOI: 10.1007/s00726-007-0020-7
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards