Component
Rod outer-segment free calcium concentration
Rod outer-segment free calcium concentration; measured endpoint and experimental scope are stated in linked claims.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Rod calcium-flux recordings showed that illumination reduces outer-segment free calcium as entry falls while extrusion continues.
Experimental context and source evidence
- cross_nutrient
- The vitamin A chromophore-initiated electrical response changes calcium signaling inside the rod.
- experimental_model
- Calcium influx/efflux measurements during illumination
- limitations
- Not a claim that dietary calcium intake determines rod calcium transients.
- nutrient_topic
- Vitamin A research collection; topical membership is not evidence of a direct dietary effect. · Vitamin A
- organism
- Bufo marinus
- plain_language
- The light response lowers intracellular calcium, providing a recovery signal.
- primary_references
- [yau-1985] Light-induced reduction of cytoplasmic free calcium in retinal rod outer segment (1985). https://pubmed.ncbi.nlm.nih.gov/2578628/ DOI: 10.1038/313579a0
- tissue_or_cell_type
- Rod outer segment
Vitamin A: forms, mechanisms, deficiency and excess (2026-09-17) · lines 949–959
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Calcium influx/efflux measurements during illumination · source_derived_draft · unverified_draft
### a-vision-light-calcium Rod calcium-flux recordings showed that illumination reduces outer-segment free calcium as entry falls while extrusion continues. Condition category: normal nutrient_topic: Vitamin A research collection; topical membership is not evidence of a direct dietary effect. plain_language: The light response lowers intracellular calcium, providing a recovery signal. organism: Bufo marinus tissue_or_cell_type: Rod outer segment experimental_model: Calcium influx/efflux measurements during illumination limitations: Not a claim that dietary calcium intake determines rod calcium transients. cross_nutrient: The vitamin A chromophore-initiated electrical response changes calcium signaling inside the rod. [yau-1985] Light-induced reduction of cytoplasmic free calcium in retinal rod outer segment (1985). https://pubmed.ncbi.nlm.nih.gov/2578628/ DOI: 10.1038/313579a0
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.