Component
Low n-3 fatty-acid intake in the rhesus photodamage study
Low n-3 fatty-acid intake in the rhesus photodamage study. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
Low n-3 intake increased parafoveal damage sensitivity relative to adequate n-3 intake.
Experimental context and source evidence
- availability_state
- nutrient_deficiency Imported condition classification; unverified.
- evidence_span
- {"source_cache": "artifacts/lutein-research/21245404.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "74fa1a576a92084789e1a2d4afcd7c657e9ef2acaf9b0a6eaca46d543447ee2b", "start_char": 0, "end_char": 1712, "text_sha256": "74fa1a576a92084789e1a2d4afcd7c657e9ef2acaf9b0a6eaca46d543447ee2b"}
- experimental_model
- Dietary deprivation/repletion and controlled laser challenge
- exposure
- Eight lifelong xanthophyll-deprived animals, n-3 intake strata; 22–28 weeks L or Z; 476-nm exposures
- limitations
- Extreme animal depletion and laser injury are not a defined human deficiency syndrome or ordinary screen exposure.
- nutrient_topic
- Lutein research collection; topical membership is not evidence of a direct dietary effect. · Lutein
- organism
- Rhesus macaque
- plain_language
- The fatty-acid effect occurred in a different retinal region.
- primary_references
- [lutein-p21245404] Nutritional manipulation of primate retinas, V: effects of lutein, zeaxanthin, and n-3 fatty acids on retinal sensitivity to blue-light-induced damage. (2011). https://pubmed.ncbi.nlm.nih.gov/21245404/ DOI: 10.1167/iovs.10-5898
- tissue_or_cell_type
- Foveal and parafoveal retina
- trigger_kind
- nutrient_deficiency Imported condition classification; unverified.
Lutein: metabolism, signaling and nutrient connections (2026-09-17) · lines 463–474
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Dietary deprivation/repletion and controlled laser challenge · source_derived_draft · unverified_draft
### lutein-n3-region Low n-3 intake increased parafoveal damage sensitivity relative to adequate n-3 intake. Condition category: nutrient_deficiency nutrient_topic: Lutein research collection; topical membership is not evidence of a direct dietary effect. plain_language: The fatty-acid effect occurred in a different retinal region. organism: Rhesus macaque tissue_or_cell_type: Foveal and parafoveal retina experimental_model: Dietary deprivation/repletion and controlled laser challenge limitations: Extreme animal depletion and laser injury are not a defined human deficiency syndrome or ordinary screen exposure. exposure: Eight lifelong xanthophyll-deprived animals, n-3 intake strata; 22–28 weeks L or Z; 476-nm exposures evidence_span: {"source_cache": "artifacts/lutein-research/21245404.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "74fa1a576a92084789e1a2d4afcd7c657e9ef2acaf9b0a6eaca46d543447ee2b", "start_char": 0, "end_char": 1712, "text_sha256": "74fa1a576a92084789e1a2d4afcd7c657e9ef2acaf9b0a6eaca46d543447ee2b"} [lutein-p21245404] Nutritional manipulation of primate retinas, V: effects of lutein, zeaxanthin, and n-3 fatty acids on retinal sensitivity to blue-light-induced damage. (2011). https://pubmed.ncbi.nlm.nih.gov/21245404/ DOI: 10.1167/iovs.10-5898
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.