Component
Polyunsaturated fatty acids
Polyunsaturated fatty acids. Read linked claims for the population, experiment and limits.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
Where it participates (unsigned role)
No infant developed clinical or hematological vitamin E-deficiency signs during the ten-week trial when feeds maintained the reported E:PUFA balance and no supplemental iron was given.
Experimental context and source evidence
- cross_nutrient
- true
- experimental_model
- Ten-week double-blind feeding trial; 42 premature infants
- exposure
- Placebo, 5 or 15 mg/day extra vitamin E; all feeds had E:PUFA at least 0.6, and no supplemental iron was given.
- limitations
- These findings are bounded by the contemporary feeds and absence of supplemental iron; they do not refute hemolysis in actual vitamin E deficiency. The design does not isolate iron as a causal modifier or establish the reported ratio as a universal recommendation.
- nutrient_topic
- Vitamin E research collection; topical membership is not evidence of a direct dietary effect. · Vitamin E
- organism
- Homo sapiens
- plain_language
- Early anemia was not automatically a vitamin E-shortage syndrome under these feeding conditions.
- primary_references
- [e-clin-neonatal1987] The early anaemia of the premature infant: is there a place for vitamin E supplementation? (1986). https://pubmed.ncbi.nlm.nih.gov/3676185/ DOI: 10.1079/bjn19860090
- tissue_or_cell_type
- Blood and erythrocytes
Vitamin E: transport, membrane protection and nutrient interactions (2026-09-17) · lines 1219–1230
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Ten-week double-blind feeding trial; 42 premature infants · source_derived_draft · unverified_draft
### e-clin-adequate-infant-feeds No infant developed clinical or hematological vitamin E-deficiency signs during the ten-week trial when feeds maintained the reported E:PUFA balance and no supplemental iron was given. Condition category: normal nutrient_topic: Vitamin E research collection; topical membership is not evidence of a direct dietary effect. plain_language: Early anemia was not automatically a vitamin E-shortage syndrome under these feeding conditions. organism: Homo sapiens tissue_or_cell_type: Blood and erythrocytes experimental_model: Ten-week double-blind feeding trial; 42 premature infants limitations: These findings are bounded by the contemporary feeds and absence of supplemental iron; they do not refute hemolysis in actual vitamin E deficiency. The design does not isolate iron as a causal modifier or establish the reported ratio as a universal recommendation. exposure: Placebo, 5 or 15 mg/day extra vitamin E; all feeds had E:PUFA at least 0.6, and no supplemental iron was given. cross_nutrient: true [e-clin-neonatal1987] The early anaemia of the premature infant: is there a place for vitamin E supplementation? (1986). https://pubmed.ncbi.nlm.nih.gov/3676185/ DOI: 10.1079/bjn19860090
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.