Component
Plasma FMN concentration
Measured process or biological entity; consult each linked claim for the experimental scope.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
Where it participates (unsigned role)
Critically ill patients had higher plasma riboflavin and FMN but lower plasma and red-cell FAD than healthy controls; plasma-vitamer relationships were disrupted.
Experimental context and source evidence
- availability_state
- biomarker_context Imported condition classification; unverified.
- experimental_model
- 119 healthy controls and 125 critically ill patients at admission; repeat measurements in 60 patients.
- exposure
- Observational HPLC plasma and red-cell riboflavin, FMN andFAD; no isolated treatment.
- limitations
- Observational illness comparison cannot diagnose tissue deficiency or establish that supplementation improves outcomes.
- nutrient_topic
- Riboflavin research collection; topical membership is not evidence of a direct dietary effect. · Riboflavin (vitamin B2)
- organism
- Homo sapiens
- plain_language
- A high circulating B2 concentration during critical illness can coexist with a lower measured cellular FAD pool.
- primary_references
- [b2-ventura2010] Relation between riboflavin, flavin mononucleotide and flavin adenine dinucleotide concentrations in plasma and red cells in patients with critical illness (2010). https://pubmed.ncbi.nlm.nih.gov/20667447/ DOI: 10.1016/j.cca.2010.07.024
- tissue_or_cell_type
- Human clinical setting
- trigger_kind
- biomarker_context Imported condition classification; unverified.
Riboflavin: mechanisms, deficiency and nutrient interactions (2026-09-17) · lines 1641–1651
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · 119 healthy controls and 125 critically ill patients at admission; repeat measurements in 60 patients. · source_derived_draft · unverified_draft
### b2-critical-illness-pools Critically ill patients had higher plasma riboflavin and FMN but lower plasma and red-cell FAD than healthy controls; plasma-vitamer relationships were disrupted. Condition category: biomarker_context nutrient_topic: Riboflavin research collection; topical membership is not evidence of a direct dietary effect. plain_language: A high circulating B2 concentration during critical illness can coexist with a lower measured cellular FAD pool. organism: Homo sapiens tissue_or_cell_type: Human clinical setting experimental_model: 119 healthy controls and 125 critically ill patients at admission; repeat measurements in 60 patients. limitations: Observational illness comparison cannot diagnose tissue deficiency or establish that supplementation improves outcomes. exposure: Observational HPLC plasma and red-cell riboflavin, FMN andFAD; no isolated treatment. [b2-ventura2010] Relation between riboflavin, flavin mononucleotide and flavin adenine dinucleotide concentrations in plasma and red cells in patients with critical illness (2010). https://pubmed.ncbi.nlm.nih.gov/20667447/ DOI: 10.1016/j.cca.2010.07.024
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.