Component
Plasma albumin concentration
Plasma albumin concentration; read each linked claim for the measured context and model.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
Plasma zinc correlated with plasma albumin in the cirrhosis and malabsorption groups, supporting albumin as one contributor to lower measured circulating zinc.
Experimental context and source evidence
- availability_state
- biomarker_context Imported condition classification; unverified.
- cross_nutrient
- Human serum albumin (carrier_protein)
- evidence_location
- Indexed primary abstract.
- evidence_span
- {"source_cache": "artifacts/zinc-clinical-sources/walker1973.abstract.txt", "locator": "Primary indexed abstract; complete local file", "file_sha256": "350425d75c9023c5b9ddb97d734e320b4e07c6fe5b834213defb1adc7cc26b00", "utf8_bytes": 991}
- experimental_model
- Observational comparison of 19 malabsorption patients, 21 cirrhosis patients, 20 controls and 23 other disease patients
- exposure
- Fasting and post-meal plasma samples; disease-group comparisons.
- limitations
- Correlations cannot distinguish dietary shortage from albumin binding, redistribution and disease effects. Plasma measurements are not intracellular zinc thresholds.
- nutrient_topic
- Zinc research collection; topical membership is not evidence of a direct dietary effect. · Zinc
- organism
- Homo sapiens
- plain_language
- A lower carrier-protein level can help explain a lower plasma zinc reading.
- primary_references
- [zn-clin-walker1973] Plasma and urinary zinc in patients with malabsorption syndromes or hepatic cirrhosis. (1973). https://pubmed.ncbi.nlm.nih.gov/4785284/ DOI: 10.1136/gut.14.12.943
- tissue_or_cell_type
- Plasma and urine
- trigger_kind
- biomarker_context Imported condition classification; unverified.
Zinc: transport, enzyme loading, deficiency and nutrient interactions (2026-09-17) · lines 1452–1465
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Observational comparison of 19 malabsorption patients, 21 cirrhosis patients, 20 controls and 23 other disease patients · source_derived_draft · unverified_draft
### zn-clin-plasma-albumin Plasma zinc correlated with plasma albumin in the cirrhosis and malabsorption groups, supporting albumin as one contributor to lower measured circulating zinc. Condition category: biomarker_context nutrient_topic: Zinc research collection; topical membership is not evidence of a direct dietary effect. plain_language: A lower carrier-protein level can help explain a lower plasma zinc reading. organism: Homo sapiens tissue_or_cell_type: Plasma and urine experimental_model: Observational comparison of 19 malabsorption patients, 21 cirrhosis patients, 20 controls and 23 other disease patients limitations: Correlations cannot distinguish dietary shortage from albumin binding, redistribution and disease effects. Plasma measurements are not intracellular zinc thresholds. exposure: Fasting and post-meal plasma samples; disease-group comparisons. cross_nutrient: Human serum albumin (carrier_protein) evidence_location: Indexed primary abstract. evidence_span: {"source_cache": "artifacts/zinc-clinical-sources/walker1973.abstract.txt", "locator": "Primary indexed abstract; complete local file", "file_sha256": "350425d75c9023c5b9ddb97d734e320b4e07c6fe5b834213defb1adc7cc26b00", "utf8_bytes": 991} [zn-clin-walker1973] Plasma and urinary zinc in patients with malabsorption syndromes or hepatic cirrhosis. (1973). https://pubmed.ncbi.nlm.nih.gov/4785284/ DOI: 10.1136/gut.14.12.943
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.