Component
Death during open-water immersion
Death during open-water immersion. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
The review concludes that the cold-shock response can result in death or serious incapacitation long before general hypothermia develops, and is probably responsible for the majority of annual open-water immersion deaths.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/cold-research/2691172.abstract.txt", "locator": "Indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "f0ea32b8c041aaf1636ae487f2f557e600a778d5eb76bad44c2edfe70c368714", "start_char": 0, "end_char": 293, "text_sha256": "f0ea32b8c041aaf1636ae487f2f557e600a778d5eb76bad44c2edfe70c368714"}
- experimental_model
- Review of the initial responses to cold-water immersion and their role in immersion deaths
- exposure
- Sudden immersion in cold water
- limitations
- A narrative review, recorded as the framing source for the cold shock response. Its mortality attribution is an inference from the response, not a trial.
- nutrient_topic
- Cold water immersion research collection; topical membership is not evidence of a direct clinical effect, and a therapeutic exposure is not a dietary intake. · Cold water immersion
- organism
- Human
- plain_language
- The dangerous part of cold water is the first minute, not the slow chill.
- primary_references
- [cold-p2691172] The initial responses to cold-water immersion in man. (1989). https://pubmed.ncbi.nlm.nih.gov/2691172/ DOI: 10.1042/cs0770581
- tissue_or_cell_type
- Respiratory and cardiovascular system
Cold water immersion: cold sensing, heat production, the catecholamine axis and what repeated exposure changes (2026-09-19) · lines 130–141
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Review of the initial responses to cold-water immersion and their role in immersion deaths · source_derived_draft · unverified_draft
### cold-cold-shock-lethality The review concludes that the cold-shock response can result in death or serious incapacitation long before general hypothermia develops, and is probably responsible for the majority of annual open-water immersion deaths. Condition category: normal nutrient_topic: Cold water immersion research collection; topical membership is not evidence of a direct clinical effect, and a therapeutic exposure is not a dietary intake. plain_language: The dangerous part of cold water is the first minute, not the slow chill. organism: Human tissue_or_cell_type: Respiratory and cardiovascular system experimental_model: Review of the initial responses to cold-water immersion and their role in immersion deaths limitations: A narrative review, recorded as the framing source for the cold shock response. Its mortality attribution is an inference from the response, not a trial. exposure: Sudden immersion in cold water evidence_span: {"source_cache": "artifacts/cold-research/2691172.abstract.txt", "locator": "Indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "f0ea32b8c041aaf1636ae487f2f557e600a778d5eb76bad44c2edfe70c368714", "start_char": 0, "end_char": 293, "text_sha256": "f0ea32b8c041aaf1636ae487f2f557e600a778d5eb76bad44c2edfe70c368714"} [cold-p2691172] The initial responses to cold-water immersion in man. (1989). https://pubmed.ncbi.nlm.nih.gov/2691172/ DOI: 10.1042/cs0770581
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.