Component
Muscle strength response to resistance training
Muscle strength response to resistance training. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Bench-press and squat gains were greater with creatine than placebo during training: approximately 24% versus 16% and 32% versus 24%, respectively.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/creatine-research/10449017.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "945065c1e6c32f344bfc4092d1306d6ebed2354e688efe65bd73702af096729e", "start_char": 0, "end_char": 1770, "text_sha256": "945065c1e6c32f344bfc4092d1306d6ebed2354e688efe65bd73702af096729e"}
- experimental_model
- Twelve-week randomized resistance-training trial
- exposure
- 25 g/day creatine for one week then 5 g/day, with standardized resistance training
- limitations
- Small male training study; mechanistic explanations for greater training adaptation are hypotheses, not directly established signaling pathways.
- nutrient_topic
- Creatine research collection; topical membership is not evidence of a direct dietary effect. · Creatine
- organism
- 19 resistance-trained men
- plain_language
- Creatine improved the measured training response in this group.
- primary_references
- [creatine-p10449017] Performance and muscle fiber adaptations to creatine supplementation and heavy resistance training. (1999). https://pubmed.ncbi.nlm.nih.gov/10449017/ DOI: 10.1097/00005768-199908000-00011
- tissue_or_cell_type
- Muscle performance and muscle biopsies
Creatine: synthesis, transport, phosphocreatine energetics and nutrient interactions (2026-09-17) · lines 971–982
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Twelve-week randomized resistance-training trial · source_derived_draft · unverified_draft
### creatine-training-strength Bench-press and squat gains were greater with creatine than placebo during training: approximately 24% versus 16% and 32% versus 24%, respectively. Condition category: normal nutrient_topic: Creatine research collection; topical membership is not evidence of a direct dietary effect. plain_language: Creatine improved the measured training response in this group. organism: 19 resistance-trained men tissue_or_cell_type: Muscle performance and muscle biopsies experimental_model: Twelve-week randomized resistance-training trial limitations: Small male training study; mechanistic explanations for greater training adaptation are hypotheses, not directly established signaling pathways. exposure: 25 g/day creatine for one week then 5 g/day, with standardized resistance training evidence_span: {"source_cache": "artifacts/creatine-research/10449017.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "945065c1e6c32f344bfc4092d1306d6ebed2354e688efe65bd73702af096729e", "start_char": 0, "end_char": 1770, "text_sha256": "945065c1e6c32f344bfc4092d1306d6ebed2354e688efe65bd73702af096729e"} [creatine-p10449017] Performance and muscle fiber adaptations to creatine supplementation and heavy resistance training. (1999). https://pubmed.ncbi.nlm.nih.gov/10449017/ DOI: 10.1097/00005768-199908000-00011
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.