Component
Skeletal-muscle microvascular perfusion
Skeletal-muscle microvascular perfusion. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Despite higher arginine, blood flow and muscle microvascular perfusion did not differ between treatments.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/citrulline-research/24824653.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "3c9cb88e6978c602b77415910ae94823f258788387d0623bfe89af339fed5ebb", "start_char": 0, "end_char": 1815, "text_sha256": "3c9cb88e6978c602b77415910ae94823f258788387d0623bfe89af339fed5ebb"}
- experimental_model
- Postexercise feeding and tracer study
- exposure
- 15 g whey plus 10 g citrulline or nonessential amino acids; comparator 45 g whey
- limitations
- Different population, protein background and protein fraction from the low-protein pilot; no automatic claim of contradiction.
- nutrient_topic
- Citrulline research collection; topical membership is not evidence of a direct dietary effect. · L-Citrulline
- organism
- Human, 21 men aged 65-80
- plain_language
- Higher blood arginine was not enough to improve measured muscle perfusion.
- primary_references
- [citrulline-p24824653] Citrulline does not enhance blood flow, microvascular circulation, or myofibrillar protein synthesis in elderly men at rest or following exercise. (2014). https://pubmed.ncbi.nlm.nih.gov/24824653/ DOI: 10.1152/ajpendo.00096.2014
- tissue_or_cell_type
- Rested and exercised skeletal muscle
Citrulline: arginine recycling, nitrogen disposal and nutrient connections (2026-09-17) · lines 1074–1085
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Postexercise feeding and tracer study · source_derived_draft · unverified_draft
### citrulline-older-perfusion-null Despite higher arginine, blood flow and muscle microvascular perfusion did not differ between treatments. Condition category: normal nutrient_topic: Citrulline research collection; topical membership is not evidence of a direct dietary effect. plain_language: Higher blood arginine was not enough to improve measured muscle perfusion. organism: Human, 21 men aged 65-80 tissue_or_cell_type: Rested and exercised skeletal muscle experimental_model: Postexercise feeding and tracer study limitations: Different population, protein background and protein fraction from the low-protein pilot; no automatic claim of contradiction. exposure: 15 g whey plus 10 g citrulline or nonessential amino acids; comparator 45 g whey evidence_span: {"source_cache": "artifacts/citrulline-research/24824653.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "3c9cb88e6978c602b77415910ae94823f258788387d0623bfe89af339fed5ebb", "start_char": 0, "end_char": 1815, "text_sha256": "3c9cb88e6978c602b77415910ae94823f258788387d0623bfe89af339fed5ebb"} [citrulline-p24824653] Citrulline does not enhance blood flow, microvascular circulation, or myofibrillar protein synthesis in elderly men at rest or following exercise. (2014). https://pubmed.ncbi.nlm.nih.gov/24824653/ DOI: 10.1152/ajpendo.00096.2014
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.