Component
Linoleoylethanolamide
Linoleoylethanolamide. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
Where it participates (unsigned role)
The olive oil diet increased brain anandamide and oleoylethanolamide without changing tissue fatty acid composition and without changing 2-arachidonoylglycerol, while the safflower oil diet increased linoleoylethanolamide and linoleic acid in brain, jejunum and liver.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/thc-research/18316044.abstract.txt", "locator": "Indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fa2ad40ef984af77cc4c50a6126ce53354a2fd56fe6fada84871e2382cef07b3", "start_char": 0, "end_char": 1668, "text_sha256": "fa2ad40ef984af77cc4c50a6126ce53354a2fd56fe6fada84871e2382cef07b3"}
- experimental_model
- Rats fed five different dietary fats with tissue endocannabinoid and fatty acid measurement
- exposure
- Short-term feeding of palm, olive, safflower, fish or arachidonic acid enriched diets
- limitations
- A five-arm dietary comparison measuring the mediators directly. Short-term feeding, and some changes occurred without any change in tissue fatty acid composition.
- nutrient_topic
- THC research collection; topical membership is not evidence of a direct clinical effect, and THC is recorded separately from the endocannabinoids it imitates. · Delta-9-tetrahydrocannabinol / THC
- organism
- Rat
- plain_language
- Which fat is eaten changes which of these messengers the brain has, sometimes without changing the tissue fat itself.
- primary_references
- [thc-p18316044] Influence of dietary fatty acids on endocannabinoid and N-acylethanolamine levels in rat brain, liver and small intestine. (2008). https://pubmed.ncbi.nlm.nih.gov/18316044/ DOI: 10.1016/j.bbalip.2008.01.006
- tissue_or_cell_type
- Brain, liver and small intestine
THC: the cannabinoid receptors, the endocannabinoid system it occupies, what the drug does, and the dietary fat it is built from (2026-09-21) · lines 660–671
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Rats fed five different dietary fats with tissue endocannabinoid and fatty acid measurement · source_derived_draft · unverified_draft
### thc-diet-shapes-endocannabinoids The olive oil diet increased brain anandamide and oleoylethanolamide without changing tissue fatty acid composition and without changing 2-arachidonoylglycerol, while the safflower oil diet increased linoleoylethanolamide and linoleic acid in brain, jejunum and liver. Condition category: normal nutrient_topic: THC research collection; topical membership is not evidence of a direct clinical effect, and THC is recorded separately from the endocannabinoids it imitates. plain_language: Which fat is eaten changes which of these messengers the brain has, sometimes without changing the tissue fat itself. organism: Rat tissue_or_cell_type: Brain, liver and small intestine experimental_model: Rats fed five different dietary fats with tissue endocannabinoid and fatty acid measurement limitations: A five-arm dietary comparison measuring the mediators directly. Short-term feeding, and some changes occurred without any change in tissue fatty acid composition. exposure: Short-term feeding of palm, olive, safflower, fish or arachidonic acid enriched diets evidence_span: {"source_cache": "artifacts/thc-research/18316044.abstract.txt", "locator": "Indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fa2ad40ef984af77cc4c50a6126ce53354a2fd56fe6fada84871e2382cef07b3", "start_char": 0, "end_char": 1668, "text_sha256": "fa2ad40ef984af77cc4c50a6126ce53354a2fd56fe6fada84871e2382cef07b3"} [thc-p18316044] Influence of dietary fatty acids on endocannabinoid and N-acylethanolamine levels in rat brain, liver and small intestine. (2008). https://pubmed.ncbi.nlm.nih.gov/18316044/ DOI: 10.1016/j.bbalip.2008.01.006
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.