Component
Small-intestinal mucosal GSH/GSSG ratio
Small-intestinal mucosal GSH/GSSG ratio. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
The cystine-theanine mixture restored the intestinal GSH/GSSG ratio during 5-fluorouracil exposure.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/theanine-research/34922485.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "5828410d2c083fec47a3c7e1907b801a2dc616dbbb7e5ed36e59d503bceeb282", "start_char": 0, "end_char": 1703, "text_sha256": "5828410d2c083fec47a3c7e1907b801a2dc616dbbb7e5ed36e59d503bceeb282"}
- experimental_model
- Chemotherapy-associated intestinal injury experiment
- exposure
- Cystine plus theanine during 5-fluorouracil exposure
- limitations
- Combination product, not isolated theanine. Preservation of antitumor activity in the tested model does not establish compatibility with every human chemotherapy regimen.
- nutrient_topic
- L-Theanine research collection; topical membership is not evidence of a direct dietary effect. · L-Theanine
- organism
- Mice
- plain_language
- This result belongs to the tested two-ingredient mixture and its chemotherapy context.
- primary_references
- [theanine-p34922485] Oral administration of cystine and theanine attenuates 5-fluorouracil-induced intestinal mucositis and diarrhea by suppressing both glutathione level decrease and ROS production in the small intestine of mucositis mouse model. (2021). https://pubmed.ncbi.nlm.nih.gov/34922485/ DOI: 10.1186/s12885-021-09057-z
- tissue_or_cell_type
- Intestinal redox balance and crypt injury
L-Theanine: metabolism, neural signaling, nutrient connections and human outcomes (2026-09-17) · lines 757–768
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Chemotherapy-associated intestinal injury experiment · source_derived_draft · unverified_draft
### theanine-ct-redox The cystine-theanine mixture restored the intestinal GSH/GSSG ratio during 5-fluorouracil exposure. Condition category: normal nutrient_topic: L-Theanine research collection; topical membership is not evidence of a direct dietary effect. plain_language: This result belongs to the tested two-ingredient mixture and its chemotherapy context. organism: Mice tissue_or_cell_type: Intestinal redox balance and crypt injury experimental_model: Chemotherapy-associated intestinal injury experiment limitations: Combination product, not isolated theanine. Preservation of antitumor activity in the tested model does not establish compatibility with every human chemotherapy regimen. exposure: Cystine plus theanine during 5-fluorouracil exposure evidence_span: {"source_cache": "artifacts/theanine-research/34922485.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "5828410d2c083fec47a3c7e1907b801a2dc616dbbb7e5ed36e59d503bceeb282", "start_char": 0, "end_char": 1703, "text_sha256": "5828410d2c083fec47a3c7e1907b801a2dc616dbbb7e5ed36e59d503bceeb282"} [theanine-p34922485] Oral administration of cystine and theanine attenuates 5-fluorouracil-induced intestinal mucositis and diarrhea by suppressing both glutathione level decrease and ROS production in the small intestine of mucositis mouse model. (2021). https://pubmed.ncbi.nlm.nih.gov/34922485/ DOI: 10.1186/s12885-021-09057-z
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.