Component
Blood-pressure readout in the 2023 Vascanox open-label study
Context-specific entity; species, compartment and exposure are stated on each claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
An uncontrolled 12-person nitrate/garlic combination study reported lower systolic pressure after two weeks, persisting at four weeks.
Experimental context and source evidence
- acting_entity
- vascanox-hp-2023
- dose
- Vascanox HP combination; constituent doses not retrieved
- duration
- Four weeks
- evidence_access
- Primary abstract
- experimental_comparison
- Within-person baseline; no placebo or factorial comparison
- experimental_model
- Twelve participants completing an open-label combination study
- interpretation_status
- Source-derived research curation; not independent primary verification
- limitations
- No placebo or ingredient-factorial arms: cannot establish SAC contribution, nitrate contribution, interaction or synergy.
- nutrient_topic
- S-allylcysteine collection; species, compartment, exposure, co-substrates and manipulation remain explicit. · S-allyl-L-cysteine / SAC
- organism
- Homo sapiens
- plain_language
- A cross-compound human lead remains available without assigning the effect to SAC.
- primary_references
- [37849591] Effects of S-Allylcysteine-Rich Garlic Extract and Dietary Inorganic Nitrate Formula on Blood Pressure and Salivary Nitric Oxide: An Open-Label Clinical Trial Among Hypertensive Subjects. · 2023 · https://pubmed.ncbi.nlm.nih.gov/37849591/ · DOI 10.7759/cureus.45369
- route
- Oral
- tissue_or_cell_type
- Twelve participants completing an open-label combination study
S-allylcysteine: sulfur signaling, redox responses and cross-nutrient mechanisms (2026-09-20) · lines 455–462
AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text. · supports · Twelve participants completing an open-label combination study · source_derived_draft · unverified_draft
## s-allylcysteine-nitrate-combination A cross-compound human lead remains available without assigning the effect to SAC. An uncontrolled 12-person nitrate/garlic combination study reported lower systolic pressure after two weeks, persisting at four weeks. Model: Twelve participants completing an open-label combination study Limitations: No placebo or ingredient-factorial arms: cannot establish SAC contribution, nitrate contribution, interaction or synergy. Evidence access: Primary abstract [37849591] Effects of S-Allylcysteine-Rich Garlic Extract and Dietary Inorganic Nitrate Formula on Blood Pressure and Salivary Nitric Oxide: An Open-Label Clinical Trial Among Hypertensive Subjects. · 2023 · https://pubmed.ncbi.nlm.nih.gov/37849591/ · DOI 10.7759/cureus.45369 Structured context: {"organism": "Homo sapiens", "tissue_or_cell_type": "Twelve participants completing an open-label combination study", "dose": "Vascanox HP combination; constituent doses not retrieved", "duration": "Four weeks", "route": "Oral", "experimental_comparison": "Within-person baseline; no placebo or factorial comparison", "acting_entity": "vascanox-hp-2023", "interpretation_status": "Source-derived research curation; not independent primary verification"}
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.